CYP2A6 anticorps

N° du produit ABIN1944821

Détail du produit anti-CYP2A6 anticorps

Antigène: CYP2A6 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYP2A6 est non-conjugé

Application: Western Blotting (WB)

Isotype: IgG1

Information d'application

Indications d'application: WB: 1:500-1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Stock: 4 °C,-20 °C

Références pour anticorps anti-CYP2A6 (ABIN1944821)

Yamano, Tatsuno, Gonzalez: "The CYP2A3 gene product catalyzes coumarin 7-hydroxylation in human liver microsomes." dans: Biochemistry, Vol. 29, Issue 5, pp. 1322-9, (1990) (PubMed).

Miles, Bickmore, Brook, McLaren, Meehan, Wolf: "Close linkage of the human cytochrome P450IIA and P450IIB gene subfamilies: implications for the assignment of substrate specificity." dans: Nucleic acids research, Vol. 17, Issue 8, pp. 2907-17, (1989) (PubMed).

Yamano, Nagata, Yamazoe, Kato, Gelboin, Gonzalez: "cDNA and deduced amino acid sequences of human P450 IIA3 (CYP2A3)." dans: Nucleic acids research, Vol. 17, Issue 12, pp. 4888, (1989) (PubMed).

Détails sur CYP2A6

Antigène: CYP2A6 (Cytochrome P450, Family 2, Subfamily A, Polypeptide 6 (CYP2A6))

Autre désignation: Cytochrome P450 2A6 (CYP2A6 Produits)

Synonymes: anticorps CPA6, anticorps CYP2A, anticorps CYP2A3, anticorps CYPIIA6, anticorps P450C2A, anticorps P450PB, anticorps cyp2a6, anticorps cytochrome P450 family 2 subfamily A member 6, anticorps cytochrome P450 2A6, anticorps cytochrome P450 family 2 subfamily A member 6 L homeolog, anticorps CYP2A6, anticorps cyp2a6.L

Sujet: Exhibits a high coumarin 7-hydroxylase activity. Can act in the hydroxylation of the anti-cancer drugs cyclophosphamide and ifosphamide. Competent in the metabolic activation of aflatoxin B1. Constitutes the major nicotine C-oxidase. Acts as a 1,4- cineole 2-exo-monooxygenase. Possesses low phenacetin O- deethylation activity.

Poids moléculaire: 56501 Da

ID gène: 1548

UniProt: P11509