Integrin beta 2 anticorps

N° du produit ABIN1967145

Cet anticorps anti-Integrin beta 2 Monoclonal Souris (Clone MEM-148) (ABIN1967145) détecte spécifiquement Integrin beta 2 dans FACS, WB, IP et Func. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Integrin beta 2 anticorps (ABIN1967145)

Antigène: Integrin beta 2 (ITGB2)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin beta 2 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP), Functional Studies (Func)

Clone: MEM-148

Détail du produit anti-Integrin beta 2 anticorps

Specificité: Monoclonal antibody MEM-148 recognizes an epitope on CD18 which is essentially inaccessible in intact integrin molecules on resting leukocytes, but is exposed on high-affinity state of LFA-1 or on unassociated CD18. CD18 (integrin beta2 subunit, beta2 integrin) is a 90-95 kD type I transmembrane protein expressed on all leukocytes.

Purification: Protein A purified

Stérilité: Sterile filtered

Immunogène: Peripheral blood mononuclear cells.

Type of Immunogen: Cells

Isotype: IgG1

Information d'application

Indications d'application: Approved: Flo, Func, IP, WB

Usage: Flow Cytometry: Recommended dilution - 8 μg/mL. The antibody MEM-148 is excellent marker of activated myeloid cells. Western Blotting: Application note - Non-reducing conditions. Functional Application: The antibody MEM-148 induces homotypic cell aggregat

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, sterile filtered.

Conseil sur la manipulation: Do not freeze.

Stock: 4 °C

Stockage commentaire: Store at 2-8°C. Do not freeze.

Détails sur Integrin beta 2

Antigène: Integrin beta 2 (ITGB2)

Autre désignation: ITGB2 / MAC-1 / CD18

Sujet: Name/Gene ID: ITGB2
Family: Integrin

Synonyms: ITGB2, CD18 antigen, CD18, Integrin beta chain, beta 2, LCAMB, MAC-1, MFI7, MF17, Integrin beta-2, LAD, LFA-1

ID gène: 3689

Pathways: Signalisation NF-kappaB, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation