TGFB1 anticorps

N° du produit ABIN199718

L’anticorps Souris Monoclonal anti-TGFB1 a été validé pour WB, IHC, ELISA, Func et Neut. Il convient pour détecter TGFB1 dans des échantillons de Humain.

Aperçu rapide pour TGFB1 anticorps (ABIN199718)

Antigène: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TGFB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Functional Studies (Func), Neutralization (Neut)

Détail du produit anti-TGFB1 anticorps

Specificité: Western Blot demonstrated reactivity to either dimeric (25kD) or monomeric (12.5kD) molecules of TGF-b under non-reducing and reducing condition, respectively. Recognizes both human platelet-derived and recombinant TGF-b in enzyme-linked in ELISA.

Purification: Protein G purified

Immunogène: TGF-b from human platelets.

Type of Immunogen: Purified protein

Isotype: IgG1 kappa

Information d'application

Indications d'application: Approved: ELISA, Func, IHC, Neut, WB

Usage: Suitable for use in ELISA, Neutralization, Immunohistochemistry and Western Blot. Neutralization: Neutralizes TGF-b activity in vitro inhibition assay of CCL/64 cell growth and also neutralize the growth promoting action of TGF-b in the NRK-49F colony forming assays. The effect of microinjection of this MAb into one blastomere of two cell stage Xenopus embryos indicated that this antibody was able to neutralize effectively the bioactivity of TGF-b in vivo. Immunohistochemistry: Used to locate TGF-b within tissues.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.0, 40 % glycerol.

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur TGFB1

Antigène: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Autre désignation: TGFB1 / TGF Beta 1

Sujet: Name/Gene ID: TGFB1
Family: TGF beta

Synonyms: TGFB1, CED, DPD1, Diaphyseal dysplasia 1, LAP, Latency-associated peptide, TGF Beta, TGFbeta, TGF-beta 1 protein, TGF-beta-1, TGFB

ID gène: 7040

UniProt: P01137

Pathways: EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints