TGFB1 anticorps (Middle Region)

N° du produit ABIN2780306

Cet anticorps anti-TGFB1 Polyclonal Lapin (ABIN2780306) détecte spécifiquement TGFB1 dans WB, IHC et IF. L’anticorps est réactif avec des échantillons de Souris, Rat, Porc, Boeuf (Vache), Cobaye, Chien, Mouton, Cheval et Chévre.

Aperçu rapide pour TGFB1 anticorps (Middle Region) (ABIN2780306)

Antigène: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Reactivité: Souris, Rat, Porc, Boeuf (Vache), Cobaye, Chien, Mouton, Cheval, Chévre

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TGFB1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-TGFB1 anticorps

Épitope: Middle Region

Séquence: DTPEWLSFDV TGVVRQWLNQ GDGIQGFRFS AHCSCDSKDN KLHVEINGIS

Homologie: Cow: 79%, Dog: 79%, Goat: 79%, Guinea Pig: 87%, Horse: 79%, Mouse: 100%, Pig: 93%, Rat: 93%, Sheep: 79%

Attributs du produit: This is a rabbit polyclonal antibody against TGFB1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of mouse TGFB1

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 390 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur TGFB1

Antigène: TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))

Autre désignation: TGFB1

Sujet: Tgfb1 is a multifunctional protein that control proliferation, differentiation, and other functions in many cell types. Many cells synthesize TGFB1 and essentially all of them have specific receptors for this protein. It regulates the actions of many other growth factors and determines a positive or negative direction of their effects. It plays an important role in bone remodelling. It is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.
Alias Symbols: Tgfb, Tgfb-1, TGFbeta1, TGF-beta1
Protein Interaction Partner: Htra1, Nrep, Ltbp3, Col1a1, Tgfbr3, Tgfbr1, Tgfbr2, Smad4, Hdac3, Jun,
Protein Size: 390

Poids moléculaire: 43 kDa

ID gène: 21803

NCBI Accession: NM_011577, NP_035707

UniProt: P04202

Pathways: EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints