TGFB1 anticorps (Middle Region)
Aperçu rapide pour TGFB1 anticorps (Middle Region) (ABIN2780306)
Antigène
Voir toutes TGFB1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- Middle Region
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Fonction
- TGFB1 Antibody - middle region
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Séquence
- DTPEWLSFDV TGVVRQWLNQ GDGIQGFRFS AHCSCDSKDN KLHVEINGIS
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Homologie
- Cow: 79%, Dog: 79%, Goat: 79%, Guinea Pig: 87%, Horse: 79%, Mouse: 100%, Pig: 93%, Rat: 93%, Sheep: 79%
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Attributs du produit
- This is a rabbit polyclonal antibody against TGFB1. It was validated on Western Blot using a cell lysate as a positive control.
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Purification
- Affinity Purified
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Immunogène
- The immunogen is a synthetic peptide directed towards the middle region of mouse TGFB1
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Commentaires
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under ABIN8114247
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- 0.5 mg/mL
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Buffer
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- prevent freeze-thaw cycles
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Stock
- 4 °C,-20 °C
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Stockage commentaire
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- TGFB1 (Transforming Growth Factor, beta 1 (TGFB1))
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Autre désignation
- TGFB1
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Sujet
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Background Information: Tgfb1 is a multifunctional protein that control proliferation, differentiation, and other functions in many cell types. Many cells synthesize TGFB1 and essentially all of them have specific receptors for this protein. It regulates the actions of many other growth factors and determines a positive or negative direction of their effects. It plays an important role in bone remodelling. It is a potent stimulator of osteoblastic bone formation, causing chemotaxis, proliferation and differentiation in committed osteoblasts.
Gene Name: Transforming growth factor, beta 1
Alternative Symbols: Tgfb, Tgfb-1, TGFbeta, TGF-beta, TGFbeta1, TGF-beta1
Protein Name: Transforming growth factor beta-1
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Poids moléculaire
- 43kDa
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ID gène
- 21803
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NCBI Accession
- NP_035707
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UniProt
- P04202
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Pathways
- EGFR Signaling Pathway, Dopaminergic Neurogenesis, Cellular Response to Molecule of Bacterial Origin, Glycosaminoglycan Metabolic Process, Regulation of Leukocyte Mediated Immunity, Regulation of Muscle Cell Differentiation, Positive Regulation of Immune Effector Process, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Ribonucleoside Biosynthetic Process, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Protein targeting to Nucleus, Autophagy, Cancer Immune Checkpoints
Antigène
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