Insulin Receptor anticorps

N° du produit ABIN201098

L’anticorps Souris Monoclonal anti-Insulin Receptor a été validé pour Inhibition. Il convient pour détecter Insulin Receptor dans des échantillons de Humain, Boeuf (Vache), Lapin, Porc et Mouton.

Aperçu rapide pour Insulin Receptor anticorps (ABIN201098)

Antigène: Insulin Receptor (INSR)

Reactivité: Humain, Boeuf (Vache), Lapin, Porc, Mouton

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Insulin Receptor est non-conjugé

Application: Blocking Antibody (Inhibition)

Détail du produit anti-Insulin Receptor anticorps

Specificité: Recognizes a protein of 135kD, identified as the alpha subunit of human insulin receptor (IR). Its epitope localizes in exon 7/8 and shows no cross-reactivity with IGF-receptors. Species cross-reactivity: Human, bovine, porcine and sheep. Weakly reacts with rabbit. Does not react with mouse or rat.

Purification: Protein G purified

Immunogène: IM-9 lymphocytes followed by purified insulin receptor.

Type of Immunogen: Cells

Isotype: IgG1

Information d'application

Indications d'application: Approved: Inhb

Usage: Suitable for use in inhibiting insulin binding. Use antibody at 10nM.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM PBS,  pH 7.4, 0.2 % BSA, 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Détails sur Insulin Receptor

Antigène: Insulin Receptor (INSR)

Autre désignation: INSR / Insulin Receptor

Sujet: Name/Gene ID: INSR
Subfamily: Insulin receptor
Family: Protein Kinase

Synonyms: INSR, CD220, ILP receptor, Insulin receptor, IR, HHF5, CD220 antigen

ID gène: 3643

UniProt: P06213

Pathways: Signalisation NF-kappaB, Signalisation RTK, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity