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CD11b anticorps

L’anticorps Souris Monoclonal anti-CD11b a été validé pour FACS, IHC, IP et IHC (fro). Il convient pour détecter CD11b dans des échantillons de Humain, Babouin, Macaque rhésus et Cynomolgus.
N° du produit ABIN206753

Aperçu rapide pour CD11b anticorps (ABIN206753)

Antigène

Voir toutes CD11b (ITGAM) Anticorps
CD11b (ITGAM) (Integrin alpha M (ITGAM))

Reactivité

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Humain, Babouin, Macaque rhésus, Cynomolgus

Hôte

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Souris

Clonalité

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Monoclonal

Conjugué

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Cet anticorp CD11b est non-conjugé

Application

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Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • Specificité

    Recognizes the human CD11b cell surface glycoprotein, a 165kD molecule also known as the alphaM integrin, MAC-1 and CR3. This molecule is expressed as a heterodimer in association with the beta 2 integrin, and is found upon monocytes, granulocytes, NK cells and some peripheral blood lymphocytes. Blocks some functions of CD11b, although full definition is still to be completed.

    Aucune reactivité croisée

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    Purification

    Protein G purified

    Immunogène

    Rheumatoid synovial cells and human monocytes.

    Type of Immunogen: Cells

    Isotype

    IgG1
  • Indications d'application

    Approved: Flo (1:10 - 1:100), IHC, IHC-Fr (1:100 - 1:1000), IP

    Usage: Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. The epitope recognized by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. The use of acetone fixation for frozen sections is recommended.

    Commentaires

    Target Species of Antibody: Human

    Restrictions

    For Research Use only
  • Format

    Liquid

    Concentration

    Lot specific

    Buffer

    PBS, 0.09 % sodium azide.

    Agent conservateur

    Sodium azide

    Précaution d'utilisation

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing. Store undiluted.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    4°C or -20°C, Avoid freeze-thaw cycles. Store undiluted.
  • Antigène

    CD11b (ITGAM) (Integrin alpha M (ITGAM))

    Autre désignation

    ITGAM / CD11b

    Sujet

    Name/Gene ID: ITGAM
    Family: Integrin

    Synonyms: ITGAM, Antigen CD11b (p170), CD11B, CD11b antigen, CR3A, Integrin alpha-M, MAC-1, MO1A, Neutrophil adherence receptor, MAC1A, SLEB6, CR-3 alpha chain

    ID gène

    3684

    Pathways

    Apoptose, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation
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