Integrin beta 2 anticorps (Activation Site)

N° du produit ABIN210134

L’anticorps anti-Integrin beta 2 Monoclonal Souris est utilisé pour la détection de Integrin beta 2 dans des échantillons de Humain. Il a été validé pour FACS, WB et IP.

Aperçu rapide pour Integrin beta 2 anticorps (Activation Site) (ABIN210134)

Antigène: Integrin beta 2 (ITGB2)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Integrin beta 2 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunoprecipitation (IP)

Clone: MEM-148

Détail du produit anti-Integrin beta 2 anticorps

Épitope: Activation Site

Specificité: Recognizes an epitope on the human CD18 Molecule that is hidden in the CD11/CD18 heterodimer on resting cells. Clone MEM-148 binds very weakly to resting peripheral blood leukocytes and strongly to all leukocytes upon cellular activation. The epitope recognized by MEM-148 is also exposed during dissociation of the CD11/CD18 by low  pH .

Purification: Protein G purified

Immunogène: Peripheral blood mononuclear cells. (ACTIVATION EPITOPE).

Isotype: IgG1

Information d'application

Indications d'application: Approved: Flo (1:20 - 1:200), IP, WB

Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells in 100 μL. Method sheets are available on request.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS

Agent conservateur: Azide free

Stock: -20 °C

Stockage commentaire: Short term: -20°C
Long term: -20°C.

Détails sur Integrin beta 2

Antigène: Integrin beta 2 (ITGB2)

Autre désignation: ITGB2 / MAC-1 / CD18

Sujet: Name/Gene ID: ITGB2
Family: Integrin

Synonyms: ITGB2, CD18 antigen, CD18, Integrin beta chain, beta 2, LCAMB, MAC-1, MFI7, MF17, Integrin beta-2, LAD, LFA-1

ID gène: 3689

Pathways: Signalisation NF-kappaB, Activation of Innate immune Response, Toll-Like Receptors Cascades, Activated T Cell Proliferation