CD36 anticorps

N° du produit ABIN210200

L’anticorps Souris Monoclonal anti-CD36 a été validé pour FACS, WB, IHC, IP, Func et IHC (fro). Il convient pour détecter CD36 dans des échantillons de Humain.

Aperçu rapide pour CD36 anticorps (ABIN210200)

Antigène: CD36

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD36 est non-conjugé

Application: Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Functional Studies (Func), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-CD36 anticorps

Specificité: Recognizes the CD36 antigen, an 88kD cell surface glycoprotein expressed by platelets and monocytes/macrophages and also by some microvascular endothelium and erythroid precursors. CD36 is the receptor for thrombospondin. When expressed by monocytes and macrophages, CD36 acts as a receptor for oxidized LDL and for apoptotic polymorphonuclear cells. Partially inhibits collagen induced platelet aggregation and macrophage ingestion of apoptotic human neutrophils. It has been reported that this may activate platelets as measured by fibrinogen binding, P-Selectin expression and Annexin V binding - for further details please contact our Technical Services team. This clone is also reported to block interaction of oxidized low-density lipoprotein (OXLDL) with CD36.

Purification: Ammonium sulfate precipitation

Immunogène: Human tonsil cells and peripheral blood mononuclear cells.

Type of Immunogen: Cells

Isotype: IgM

Information d'application

Indications d'application: Approved: Flo (1:25 - 1:50), Func, IHC, IHC-Fr, IP, WB

Usage: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 10^6 cells or 100 μL whole blood. Method sheets are available on request.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS.

Agent conservateur: Azide free

Détails sur CD36

Antigène: CD36

Autre désignation: CD36

Sujet: Name/Gene ID: CD36

Synonyms: CD36, Cluster determinant 36, FAT, Fatty acid translocase, Glycoprotein IIIb, gp4, GPIIIB, GPIV, PAS-4 protein, PAS IV, PASIV, Platelet collagen receptor, Platelet glycoprotein IV, SCARB3, Thrombospondin receptor, BDPLT10, CD36 antigen, CHDS7, gp3B, PAS-4, Platelet glycoprotein 4

ID gène: 948

Pathways: Signalisation TLR, Peptide Hormone Metabolism, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Lipid Metabolism by PPARalpha, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Hepatitis C, Toll-Like Receptors Cascades, Lipid Metabolism, S100 Proteins