PTK2B anticorps (AA 726-863)

N° du produit ABIN212775

Détail du produit anti-PTK2B anticorps

Antigène: PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))

Épitope: AA 726-863

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTK2B est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Specificité: Recognizes Pyk2 at 116kD in mouse brain cytosol. Also detects a band at 40kD, which may be a degradation product. Does not cross-react with FAK. Species cross-reactivity: Human and mouse.

Purification: Protein A purified

Immunogène: GST fusion protein containing aa726-863 of human Pyk2.

Type of Immunogen: Fusion protein

Isotype: IgG

Information d'application

Indications d'application: Approved: IP, WB

Usage: Suitable for use in Western Blot and Immunoprecipitation. Proteins were visualized using a goat anti-rabbit (HRP) secondary antibody and a chemiluminescence detection system. Pyk2 has a MW of approximately 116kD as calculated from the amino acid sequence deduced from the complete human cDNA. Immunoprecipitation: 4 μg detected Pyk2 from 500 μg of mouse brain cytosolic RIPA lysate.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 0.1 M Tris-glycine,  pH 7.4, 0.15 M sodium chloride, 0.05 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C
Long term: Add glycerol (40-50%) -20°C.

Détails sur PTK2B

Antigène: PTK2B (PTK2B Protein tyrosine Kinase 2 beta (PTK2B))

Autre désignation: PTK2B / PYK2 (PTK2B Produits)

Synonymes: anticorps CADTK, anticorps CAKB, anticorps FADK2, anticorps FAK2, anticorps PKB, anticorps PTK, anticorps PYK2, anticorps RAFTK, anticorps CAKbeta, anticorps E430023O05Rik, anticorps Raftk, anticorps Pyk2, anticorps fak1b, anticorps ptk2.2, anticorps ptk2b, anticorps si:ch1073-355e8.1, anticorps protein tyrosine kinase 2 beta, anticorps PTK2 protein tyrosine kinase 2 beta, anticorps protein tyrosine kinase 2aa, anticorps PTK2B, anticorps Ptk2b, anticorps ptk2aa

Sujet: Name/Gene ID: PTK2B
Subfamily: Focal Adhesion Kinase
Family: Protein Kinase

Synonyms: PTK2B, CADTK, CAKB, Cell adhesion kinase beta, FADK 2, FADK2, Focal adhesion kinase 2, FRNK, FAK2, Proline-rich tyrosine kinase 2, Protein-tyrosine kinase 2-beta, Protein kinase B, Protein tyrosine kinase 2 beta, PYK2, RAFTK, CAK-beta, PKB, PTK

ID gène: 2185

UniProt: Q14289

Pathways: EGFR Signaling Pathway, Regulation of Actin Filament Polymerization, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Cellular Glucan Metabolic Process, Cell-Cell Junction Organization, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, Positive Regulation of fat Cell Differentiation, VEGF Signaling