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ErbB2/Her2 anticorps (Cytoplasmic Domain)

ErbB2/Her2 Reactivité: Humain, Souris, Rat, Singe, Cheval, Boeuf (Vache), Hamster IHC, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN213613
  • Antigène Voir toutes ErbB2/Her2 Anticorps
    ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
    Épitope
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    Cytoplasmic Domain
    Reactivité
    • 512
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    • 34
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    • 1
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    Humain, Souris, Rat, Singe, Cheval, Boeuf (Vache), Hamster
    Hôte
    • 403
    • 156
    • 11
    • 5
    • 3
    • 3
    Lapin
    Clonalité
    • 406
    • 172
    • 2
    Polyclonal
    Conjugué
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    • 1
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    Cet anticorp ErbB2/Her2 est non-conjugé
    Application
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    Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Marque
    IHC-plus™
    Specificité
    Human ERBB2 / HER2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
    Homologie
    Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Hamster, Horse (100%) Elephant, Pig (94%) Bat (88%).
    Purification
    Immunoaffinity purified
    Immunogène
    Synthetic 17 amino acid peptide from cytoplasmic domain of human ERBB2 / HER2. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Hamster, Horse (100%), Elephant, Pig (94%), Bat (88%).

    Type of Immunogen: Synthetic peptide
    Top Product
    Discover our top product ErbB2/Her2 Anticorps primaire
  • Indications d'application
    Approved: IHC, IHC-P (10 μg/mL)

    Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.
    Commentaires

    Target Species of Antibody: Human

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    PBS, less than 0.1 % sodium azide.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C,-20 °C
    Stockage commentaire
    Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
    Date de péremption
    12 months
  • Antigène
    ErbB2/Her2 (Receptor tyrosine-protein kinase erbB-2 (ErbB2/Her2))
    Autre désignation
    ERBB2 / HER2 (ErbB2/Her2 Produits)
    Synonymes
    anticorps CD340, anticorps HER-2, anticorps HER-2/neu, anticorps HER2, anticorps MLN 19, anticorps NEU, anticorps NGL, anticorps TKR1, anticorps Erbb-2, anticorps Neu, anticorps c-erbB2, anticorps c-neu, anticorps mKIAA3023, anticorps wu:fv70f10, anticorps zgc:63601, anticorps erb2, anticorps erb-b2 receptor tyrosine kinase 2, anticorps ERBB2, anticorps Erbb2, anticorps erbb2
    Sujet
    Name/Gene ID: ERBB2
    Subfamily: EGF Receptor
    Family: Protein Kinase

    Synonyms: ERBB2, C-erb B2/neu protein, CD340, HER2, Herstatin, MLN 19, HER-2, Neu, NGL, Proto-oncogene c-ErbB-2, Proto-oncogene Neu, CD340 antigen, MLN19, p185erbB2, TKR1
    ID gène
    2064
    Pathways
    Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development
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