GPR37L1 anticorps (AA 101-200) (Alexa Fluor 488)

N° du produit ABIN2174803

Détail du produit anti-GPR37L1 anticorps (Alexa Fluor 488)

Antigène: GPR37L1 (G Protein-Coupled Receptor 37 Like 1 (GPR37L1))

Épitope: AA 101-200

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPR37L1 est conjugé à/à la Alexa Fluor 488

Application: Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Homologie: Human,Mouse

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human GPR37L1

Isotype: IgG

Information d'application

Indications d'application: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: ProClin

Précaution d'utilisation: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur GPR37L1

Antigène: GPR37L1 (G Protein-Coupled Receptor 37 Like 1 (GPR37L1))

Autre désignation: Gpr37l1 (GPR37L1 Produits)

Synonymes: anticorps GPR37L1, anticorps ET(B)R-LP-2, anticorps ETBR-LP-2, anticorps AW047233, anticorps CAG-18, anticorps D0Kist8, anticorps G protein-coupled receptor 37 like 1, anticorps G protein-coupled receptor 37-like 1, anticorps GPR37L1, anticorps Gpr37l1

Sujet:

Synonyms: Endothelin B receptor-like protein 2, ET(B)R-LP-2, ETBR-LP-2, ETBR2, ETBRLP2, G-protein coupled receptor 37-like 1, GPR37L1, ETBR2_HUMAN.

Background: G-protein coupled receptor. Has been shown to bind the neuroprotective and glioprotective factor prosaposin (PSAP), leading to endocytosis followed by an ERK phosphorylation cascade. However, other studies have shown that prosaposin does not increase activity. It has been suggested that GPR37L1 is a constitutively active receptor which signals through the guanine nucleotide-binding protein G(s) subunit alpha. Participates in the regulation of postnatal cerebellar development by modulating the Shh pathway. Regulates baseline blood pressure in females and protects against cardiovascular stress in males. Mediates inhibition of astrocyte glutamate transporters and reduction in neuronal N-methyl-D-aspartate receptor activity.

ID gène: 9283

UniProt: O60883