TYK2 anticorps (PE)

N° du produit ABIN2179903

Cet anticorps Lapin Polyclonal détecte spécifiquement TYK2 dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour TYK2 anticorps (PE) (ABIN2179903)

Antigène: TYK2 (Tyrosine Kinase 2 (TYK2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TYK2 est conjugé à/à la PE

Application: Western Blotting (WB)

Détail du produit anti-TYK2 anticorps (PE)

Réactivité croisée: Humain

Homologie: Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogène: KLH conjugated synthetic peptide derived from human TYK2

Isotype: IgG

Information d'application

Indications d'application: FCM: (1:20-100)
Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Détails sur TYK2

Antigène: TYK2 (Tyrosine Kinase 2 (TYK2))

Autre désignation: Tyk2

Sujet:

Synonyms: JTK 1, JTK1, Non receptor tyrosine protein kinase 2, Non receptor tyrosine protein kinase TYK2, Non-receptor tyrosine-protein kinase TYK2, Protein Tyrosine Kinase 2, TYK 2, Tyk2, TYK2_HUMAN, Tyrosine kinase 2.

Background: This gene encodes a member of the tyrosine kinase and, more specifically, the Janus kinases (JAKs) protein families. This protein associates with the cytoplasmic domain of type I and type II cytokine receptors and promulgate cytokine signals by phosphorylating receptor subunits. It is also component of both the type I and type III interferon signaling pathways. As such, it may play a role in anti-viral immunity. A mutation in this gene has been associated with hyperimmunoglobulin E syndrome (HIES) - a primary immunodeficiency characterized by elevated serum immunoglobulin E. [provided by RefSeq].

ID gène: 7297

Pathways: Signalistation JAK/STAT, Hepatitis C