Insulin Receptor anticorps (Exon 7)

N° du produit ABIN228599

L’anticorps Souris Monoclonal anti-Insulin Receptor a été validé pour ELISA, IP et Func. Il convient pour détecter Insulin Receptor dans des échantillons de Humain.

Aperçu rapide pour Insulin Receptor anticorps (Exon 7) (ABIN228599)

Antigène: Insulin Receptor (INSR)

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Insulin Receptor est non-conjugé

Application: ELISA, Immunoprecipitation (IP), Functional Studies (Func)

Clone: 83-14

Détail du produit anti-Insulin Receptor anticorps

Épitope: AA 469-592, Exon 7

Specificité: Recognizes human Insulin receptor, alpha subunit. Inhibits insulin binding (~80 % ) and mimics insulin action. Weakly reacts with bovine, porcine and sheep. Does not react with rabbit, mouse and rat.

Purification: Protein A purified

Immunogène: IM-9 lymphocytes followed by purified insulin receptor. MW of Antigen: 135kD. Epitope: aa469-592 (exon 7/8). Cellular Localization: Cell membrane.

Type of Immunogen: Cells

Isotype: IgG2a kappa

Information d'application

Indications d'application: Approved: ELISA, Func, IP

Usage: Suitable for use in ELISA, Immunoprecipitation, Tyrosine Kinase Assay and Inhibition of insulin binding. May also be used as insulin-like agonist. ELISA: Both as capture and detection. Immunoprecipitation (Use Protein G): 2 μg/mg protein lysate. Tyrosine Kinase Assay: Antibody-mediated capture on microtiter plates. Positive control: IM-9 lymphocyte cells and Placenta. The applications listed have been tested for the unmodified form of this product. Other forms have not been tested.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: 10 mM PBS,  pH 7.4. Glycerol free.

Agent conservateur: Azide free

Conseil sur la manipulation: Avoid repeat freeze-thaw cycles.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur Insulin Receptor

Antigène: Insulin Receptor (INSR)

Autre désignation: INSR / Insulin Receptor

Sujet: Name/Gene ID: INSR
Subfamily: Insulin receptor
Family: Protein Kinase

Synonyms: INSR, CD220, ILP receptor, Insulin receptor, IR, HHF5, CD220 antigen

ID gène: 3643

UniProt: P06213

Pathways: Signalisation NF-kappaB, Signalisation RTK, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity