TP53INP1 anticorps

N° du produit ABIN2435140

Détail du produit anti-TP53INP1 anticorps

Antigène: TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TP53INP1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Affinity purification

Immunogène: Synthetic peptide of human TP53INP1

Isotype: IgG

Information d'application

Indications d'application: WB 1:200-1:1000, IHC 1:50-1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: PBS with 0.05 % sodium azide and 50 % glycerol, PH7.4

Agent conservateur: Sodium azide

Conseil sur la manipulation: Avoid freeze / thaw cycles.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur TP53INP1

Antigène: TP53INP1 (Tumor Protein P53 Inducible Nuclear Protein 1 (TP53INP1))

Autre désignation: TP53INP1 (TP53INP1 Produits)

Synonymes: anticorps cb1036, anticorps wu:fb70a09, anticorps wu:fi13h08, anticorps zgc:158431, anticorps TP53INP1, anticorps 2700057G22Rik, anticorps SIP, anticorps SIP18, anticorps SIP27, anticorps Stinp, anticorps Teap, anticorps TP53DINP1, anticorps TP53INP1A, anticorps TP53INP1B, anticorps p53DINP1, anticorps Trp53inp1, anticorps tumor protein p53 inducible nuclear protein 1, anticorps tumor protein p53 inducible nuclear protein 1 S homeolog, anticorps transformation related protein 53 inducible nuclear protein 1, anticorps TP53INP1, anticorps tp53inp1.S, anticorps tp53inp1, anticorps Trp53inp1, anticorps Tp53inp1

Sujet: TP53INP1 (tumor protein p53-inducible nuclear protein 1), also known as p53DINP1, SIP or Teap, is a 240 amino acid protein that localizes to nuclear bodies and exists as two alternatively spliced isoforms, designated p53DINP1a and p53DINP1b. Expressed ubiquitously with higher expression in testis, pancreas and spleen tissue, TP53INP1 functions in response to double-stranded DNA breaks and regulates p53-mediated apoptosis, specifically by phosphorylating human p53 at Ser 46, an event that leads to cell death. Additionally, TP53INP1 is thought to interact with p73 and may be involved in the regulation of p73-controlled cell cycle progression. TP53INP1 expression is downregulated in pancreatic ductal adenocarcinomas, suggesting that, via its ability to induce cell death, TP53INP1 plays a role in tumor suppression.

Poids moléculaire: Calculated MW: 27 kDa

NCBI Accession: NP_150601