Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Specificité
Detects the carboxy-terminal amino acids within the PDZ-binding domain of both the PHLPP1 alpha and beta isoforms. Detects the enzyme at around 150 kDa (alpha isoform) and 200 kDa (beta isoform) by western blot from various cell lines (THP-1) and tissues such as brain. Does not cross-react with PHLPP2.
Réactivité croisée
Souris, Rat (Rattus)
Purification
Affinity Purified
Immunogène
human PHLPP1 (amino acids 1192-1205 of the alpha isoform, or amino acids 1704-1717 of the beta isoform)