PSMD12 anticorps

N° du produit ABIN2452114

Cet anticorps Lapin Polyclonal détecte spécifiquement PSMD12 dans WB et IP. Il présente une réactivité envers Saccharomyces cerevisiae et a été mentionné dans 3+ publications.

Aperçu rapide pour PSMD12 anticorps (ABIN2452114)

Antigène: PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))

Reactivité: Saccharomyces cerevisiae

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMD12 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP)

Détail du produit anti-PSMD12 anticorps

Attributs du produit: Product: Rabbit polyclonal antibody affinity purified with recombinant Rpn5p

Purification: Affinity purified

Immunogène: Recombinant yeast Rpn5p expressed in E. coli

Isotype: IgG

Information d'application

Indications d'application: 1) Western blotting: ~1000 fold dilution
2) Immunoprecipitation Not tested for other applications

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 100 mM NaCl, 10 mM Tris-HCl pH 7.4, 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: To avoid repeated freezing and thawing, store the antibody solution in aliquots.

Stock: -20 °C

Références pour anticorps anti-PSMD12 (ABIN2452114)

Isono, Nishihara, Saeki, Yashiroda, Kamata, Ge, Ueda, Kikuchi, Tanaka, Nakano, Toh-e: "The assembly pathway of the 19S regulatory particle of the yeast 26S proteasome." dans: Molecular biology of the cell, Vol. 18, Issue 2, pp. 569-80, (2007) (PubMed).

Finley, Tanaka, Mann, Feldmann, Hochstrasser, Vierstra, Johnston, Hampton, Haber, Mccusker, Silver, Frontali, Thorsness, Varshavsky, Byers, Madura, Reed, Wolf, Jentsch, Sommer, Baumeister, Goldberg et al.: "Unified nomenclature for subunits of the Saccharomyces cerevisiae proteasome regulatory particle. ..." dans: Trends in biochemical sciences, Vol. 23, Issue 7, pp. 244-5, (1998) (PubMed).

Hershko, Ciechanover: "The ubiquitin system." dans: Annual review of biochemistry, Vol. 67, pp. 425-79, (1998) (PubMed).

Détails sur PSMD12

Antigène: PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))

Autre désignation: Rpn5

Sujet: Background: The 26 S proteasome is a protein complex with a molecular mass of 2000 kDa. It is essential not only for eliminating damaged or misfolded proteins but also for degrading short lived regulatory proteins involved in cell cycle regulation, DNA repair, signal transduction, apoptosis, and metabolic regulation. Rpn5p is essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to mammalian p55 subunit and to another S. cerevisiae regulatory subunit, Rpn7. It consists of 445 amino acids with molecular weight of 51,768.

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway