PSMD12 anticorps (Middle Region)

N° du produit ABIN2787421

Détail du produit anti-PSMD12 anticorps

Antigène: PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))

Épitope: Middle Region

Reactivité: Humain, Souris, Rat, Boeuf (Vache), Cobaye, Cheval, Chien, Poisson zèbre (Danio rerio), Lapin

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMD12 est non-conjugé

Application: Western Blotting (WB)

Séquence: KYKDLLKLFT TMELMRWSTL VEDYGMELRK GSLESPATDV FGSTEEGEKR

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 93%, Zebrafish: 85%

Attributs du produit: This is a rabbit polyclonal antibody against PSMD12. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogène: The immunogen is a synthetic peptide directed towards the middle region of human PSMD12

Information d'application

Indications d'application: Optimal working dilutions should be determined experimentally by the investigator.

Commentaires:

Antigen size: 456 AA

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze-thaw cycles.

Stock: -20 °C

Stockage commentaire: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Détails sur PSMD12

Antigène: PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))

Autre désignation: PSMD12 (PSMD12 Produits)

Synonymes: anticorps wu:fb38a06, anticorps wu:fc34f08, anticorps wu:fc49f02, anticorps PSMD12, anticorps rpn5, anticorps Rpn5, anticorps p55, anticorps 1500002F15Rik, anticorps AI480719, anticorps P55, anticorps proteasome 26S subunit, non-ATPase 12, anticorps proteasome (prosome, macropain) 26S subunit, non-ATPase, 12, anticorps psmd12, anticorps PSMD12, anticorps Psmd12

Sujet: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3.
Alias Symbols: MGC75406, p55, Rpn5
Protein Interaction Partner: FUS, HUWE1, SUMO2, UBC, PSMD14, RNF2, KIAA0368, HNRNPA0, TXNL1, SQSTM1, PSMD11, PSMD3, PSMD1, PSMC6, PSMC5, PSMC4, PSMC2, PSMC1, FLNC, FLNB, KCMF1, PARK2, BAG3, RNF11, NPM1, NOS2, PSMD6, PSMD13, PSMD7, UGGT1, PSME3, USP14, PSME1, PSMD10, PSMD8, PSMD4, PSM
Protein Size: 456

Poids moléculaire: 53 kDa

ID gène: 5718

NCBI Accession: NM_002816, NP_002807

UniProt: Q5RBI3

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway