PSMD12 anticorps (AA 276-304)

N° du produit ABIN1881697

Détail du produit anti-PSMD12 anticorps

Antigène: PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))

Épitope: AA 276-304

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMD12 est non-conjugé

Application: Western Blotting (WB)

Homologie: B

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogène: This PSMD12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 276-304 amino acids from the Central region of human PSMD12.

Clone: RB42427

Isotype: Ig Fraction

Information d'application

Indications d'application: WB: 1:1000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Date de péremption: 6 months

Références pour anticorps anti-PSMD12 (ABIN1881697)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." dans: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Gandhi, Zhong, Mathivanan, Karthick, Chandrika, Mohan, Sharma, Pinkert, Nagaraju, Periaswamy, Mishra, Nandakumar, Shen, Deshpande, Nayak, Sarker, Boeke, Parmigiani, Schultz, Bader, Pandey: "Analysis of the human protein interactome and comparison with yeast, worm and fly interaction datasets." dans: Nature genetics, Vol. 38, Issue 3, pp. 285-93, (2006) (PubMed).

Listovsky, Oren, Yudkovsky, Mahbubani, Weiss, Lebendiker, Brandeis: "Mammalian Cdh1/Fzr mediates its own degradation." dans: The EMBO journal, Vol. 23, Issue 7, pp. 1619-26, (2004) (PubMed).

Bouwmeester, Bauch, Ruffner, Angrand, Bergamini, Croughton, Cruciat, Eberhard, Gagneur, Ghidelli, Hopf, Huhse, Mangano, Michon, Schirle, Schlegl, Schwab, Stein, Bauer, Casari, Drewes, Gavin, Jackson et al.: "A physical and functional map of the human TNF-alpha/NF-kappa B signal transduction pathway. ..." dans: Nature cell biology, Vol. 6, Issue 2, pp. 97-105, (2004) (PubMed).

Détails sur PSMD12

Antigène: PSMD12 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 12 (PSMD12))

Autre désignation: PSMD12 (PSMD12 Produits)

Synonymes: anticorps wu:fb38a06, anticorps wu:fc34f08, anticorps wu:fc49f02, anticorps PSMD12, anticorps rpn5, anticorps Rpn5, anticorps p55, anticorps 1500002F15Rik, anticorps AI480719, anticorps P55, anticorps proteasome 26S subunit, non-ATPase 12, anticorps proteasome (prosome, macropain) 26S subunit, non-ATPase, 12, anticorps psmd12, anticorps PSMD12, anticorps Psmd12

Sujet: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 3.

Poids moléculaire: 52904

NCBI Accession: NP_002807, NP_777360

UniProt: O00232

Pathways: Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway