DNASE2B anticorps

N° du produit ABIN2458670

Détail du produit anti-DNASE2B anticorps

Antigène: DNASE2B (Deoxyribonuclease II beta (DNASE2B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DNASE2B est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DNASE2B.

Information d'application

Indications d'application: DNASE2B antibody can be used for detection of DNASE2B by ELISA at 1:312500. DNASE2B antibody can be used for detection of DNASE2B by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DNASE2B antibody at -20 °C.

Détails sur DNASE2B

Antigène: DNASE2B (Deoxyribonuclease II beta (DNASE2B))

Autre désignation: DNASE2B (DNASE2B Produits)

Synonymes: anticorps DNASE2, anticorps deoxyribonuclease-2-beta, anticorps DLAD, anticorps DNASE2B, anticorps dnase2b, anticorps AI526873, anticorps Dlad, anticorps DnaseIIb, anticorps UOX, anticorps deoxyribonuclease 2 beta, anticorps deoxyribonuclease II beta, anticorps DNASE2B, anticorps dnase2b, anticorps Dnase2b

Sujet: DNASE2B shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH . Unlike DNase II which is ubiquitously expressed, expression of this protein is restricted to the salivary gland and lungs. The protein encoded by this gene shares considerable sequence similarity to, and is structurally related to DNase II. The latter is a well characterized endonuclease that catalyzes DNA hydrolysis in the absence of divalent cations at acidic pH . Unlike DNase II which is ubiquitously expressed, expression of this gene product is restricted to the salivary gland and lungs. The gene has been localized to chromosome 1p22.3 adjacent (and in opposite orientation) to the uricase pseudogene. Two transcript variants encoding different isoforms have been described for this gene.

Poids moléculaire: 39 kDa

ID gène: 58511

NCBI Accession: NP_067056

UniProt: Q8WZ79