ATP2B3 anticorps

N° du produit ABIN2458839

Détail du produit anti-ATP2B3 anticorps

Antigène: ATP2B3 (ATPase, Ca++ Transporting, Plasma Membrane 3 (ATP2B3))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ATP2B3 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ATP2B3.

Information d'application

Indications d'application: ATP2B3 antibody can be used for detection of ATP2B3 by ELISA at 1:312500. ATP2B3 antibody can be used for detection of ATP2B3 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ATP2B3 antibody at -20 °C.

Détails sur ATP2B3

Antigène: ATP2B3 (ATPase, Ca++ Transporting, Plasma Membrane 3 (ATP2B3))

Autre désignation: ATP2B3 (ATP2B3 Produits)

Synonymes: anticorps PMCA3, anticorps PMCA3a, anticorps SCAX1, anticorps atp2b3, anticorps pmca3a, anticorps zgc:92885, anticorps 6430519O13Rik, anticorps Pmca3, anticorps ATPase plasma membrane Ca2+ transporting 3, anticorps ATPase, Ca++ transporting, plasma membrane 3a, anticorps ATPase, Ca++ transporting, plasma membrane 3, anticorps plasma membrane calcium-transporting ATPase 2, anticorps ATP2B3, anticorps atp2b3a, anticorps Atp2b3, anticorps atp2b3, anticorps LOC100639471

Sujet: ATP2B3 gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. ATP2B3 is the plasma membrane calcium ATPase isoform 3.The protein encoded by this gene belongs to the family of P-type primary ion transport ATPases characterized by the formation of an aspartyl phosphate intermediate during the reaction cycle. These enzymes remove bivalent calcium ions from eukaryotic cells against very large concentration gradients and play a critical role in intracellular calcium homeostasis. The mammalian plasma membrane calcium ATPase isoforms are encoded by at least four separate genes and the diversity of these enzymes is further increased by alternative splicing of transcripts. The expression of different isoforms and splice variants is regulated in a developmental, tissue- and cell type-specific manner, suggesting that these pumps are functionally adapted to the physiological needs of particular cells and tissues. This gene encodes the plasma membrane calcium ATPase isoform 3. Alternatively spliced transcript variants encoding different isoforms have been identified.

Poids moléculaire: 134 kDa

ID gène: 492

NCBI Accession: NP_001001344

UniProt: Q16720

Pathways: Ribonucleoside Biosynthetic Process