CNTNAP1 anticorps

N° du produit ABIN2458937

Détail du produit anti-CNTNAP1 anticorps

Antigène: CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CNTNAP1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CNTNAP1.

Information d'application

Indications d'application: CNTNAP1 antibody can be used for detection of CNTNAP1 by ELISA at 1:1562500. CNTNAP1 antibody can be used for detection of CNTNAP1 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CNTNAP1 antibody at -20 °C.

Détails sur CNTNAP1

Antigène: CNTNAP1 (Contactin Associated Protein 1 (CNTNAP1))

Autre désignation: CNTNAP1 (CNTNAP1 Produits)

Synonymes: anticorps CNTNAP1, anticorps CASPR, anticorps CNTNAP, anticorps NRXN4, anticorps P190, anticorps Caspr, anticorps AI841080, anticorps NCP1, anticorps Nrxn4, anticorps p190, anticorps shm, anticorps contactin associated protein 1, anticorps contactin associated protein-like 1, anticorps CNTNAP1, anticorps cntnap1, anticorps Cntnap1

Sujet: CNTNAP1 was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,384-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.The gene product was initially identified as a 190-kD protein associated with the contactin-PTPRZ1 complex. The 1,381-amino acid protein, also designated p190 or CASPR for 'contactin-associated protein,' includes an extracellular domain with several putative protein-protein interaction domains, a putative transmembrane domain, and a 74-amino acid cytoplasmic domain. Northern blot analysis showed that the gene is transcribed predominantly in brain as a transcript of 6.2 kb, with weak expression in several other tissues tested. The architecture of its extracellular domain is similar to that of neurexins, and this protein may be the signaling subunit of contactin, enabling recruitment and activation of intracellular signaling pathways in neurons.

Poids moléculaire: 156 kDa

ID gène: 8506

NCBI Accession: NP_003623

UniProt: P78357

Pathways: Cell-Cell Junction Organization