PCDHA5 anticorps

N° du produit ABIN2459279

Détail du produit anti-PCDHA5 anticorps

Antigène: PCDHA5 (Protocadherin alpha 5 (PCDHA5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDHA5 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCDHA5.

Information d'application

Indications d'application: PCDHA5 antibody can be used for detection of PCDHA5 by ELISA at 1:312500. PCDHA5 antibody can be used for detection of PCDHA5 by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PCDHA5 antibody at -20 °C.

Détails sur PCDHA5

Antigène: PCDHA5 (Protocadherin alpha 5 (PCDHA5))

Autre désignation: PCDHA5 (PCDHA5 Produits)

Synonymes: anticorps CNR6, anticorps CNRN6, anticorps CNRS6, anticorps CRNR6, anticorps PCDH-ALPHA5, anticorps Cnr6, anticorps Crnr6, anticorps rCNRv05, anticorps PCDHA5, anticorps Pcdha5, anticorps protocadherin alpha 5, anticorps protocadherin alpha-5, anticorps PCDHA5, anticorps Pcdha5, anticorps LOC100738784, anticorps LOC100847156, anticorps LOC100713870, anticorps LOC100629824

Sujet: The gene encoding PCDHA5 is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. PCDHA5 is a single-pass type I membrane protein. It contains 6 cadherin domains. PCDHA5 is a potential calcium-dependent cell-adhesion protein. It may be involved in the establishment and maintenance of specific neuronal connections in the brain.This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Poids moléculaire: 99 kDa

ID gène: 56143

NCBI Accession: NP_061731

UniProt: Q9Y5H7