DCP1B anticorps

N° du produit ABIN2459448

Détail du produit anti-DCP1B anticorps

Antigène: DCP1B (DCP1 Decapping Enzyme Homolog B (DCP1B))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DCP1B est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human DCP1B.

Information d'application

Indications d'application: DCP1B antibody can be used for detection of DCP1B by ELISA at 1:62500. DCP1B antibody can be used for detection of DCP1B by western blot at 1 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store DCP1B antibody at -20 °C.

Détails sur DCP1B

Antigène: DCP1B (DCP1 Decapping Enzyme Homolog B (DCP1B))

Autre désignation: DCP1B (DCP1B Produits)

Synonymes: anticorps DCP1, anticorps hDcp1b, anticorps B930050E02Rik, anticorps RGD1562214, anticorps dcp1, anticorps dcp1b, anticorps mitc1l, anticorps si:ch211-87p6none, anticorps decapping mRNA 1B, anticorps decapping mRNA 1B L homeolog, anticorps DCP1B, anticorps Dcp1b, anticorps dcp1b.L, anticorps dcp1b

Sujet: DCP1B may play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. It may remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP.DCP1B is a core component of the mRNA decapping complex, a key factor in the regulation of mRNA decay (Lykke-Andersen, 2002 [PubMed 12417715]).

Poids moléculaire: 68 kDa

ID gène: 196513

NCBI Accession: NP_689853

UniProt: Q8IZD4