SNF8 anticorps

N° du produit ABIN2460244

Détail du produit anti-SNF8 anticorps

Antigène: SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SNF8 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SNF8.

Information d'application

Indications d'application: SNF8 antibody can be used for detection of SNF8 by ELISA at 1:1562500. SNF8 antibody can be used for detection of SNF8 by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SNF8 antibody at -20 °C.

Détails sur SNF8

Antigène: SNF8 (Vacuolar-sorting Protein SNF8 (SNF8))

Autre désignation: SNF8 (SNF8 Produits)

Synonymes: anticorps d11moh34, anticorps vps22, anticorps Dot3, anticorps EAP30, anticorps VPS22, anticorps D11moh34, anticorps RGD1310144, anticorps D11Moh34, anticorps D11MOH34, anticorps zgc:101578, anticorps SNF8, ESCRT-II complex subunit, anticorps eap30 subunit of ell complex, putative, anticorps EAP30 subunit of ELL complex, anticorps SNF8, ESCRT-II complex subunit S homeolog, anticorps SNF8, ESCRT-II complex subunit, homolog (S. cerevisiae), anticorps snf8, anticorps TA17290, anticorps TVAG_107410, anticorps Bm1_05145, anticorps SNF8, anticorps Snf8, anticorps snf8.S

Sujet: ELL encodes an RNA polymerase II transcription factor that undergoes frequent translocation in acute myeloid leukemia (AML). In addition to its elongation activity, ELL contains a novel type of RNA polymerase II interaction domain that is capable of repressing polymerase activity in promoter-specific transcription. EAP30 is a subunit of the ELL complex. EAP30 can interact with ELL and derepress ELL's inhibitory activity in vitro.SNF8, VPS25 (MIM 610907), and VPS36 (MIM 610903) form ESCRT-II (endosomal sorting complex required for transport II), a complex involved in endocytosis of ubiquitinated membrane proteins. SNF8, VPS25, and VPS36 are also associated in a multiprotein complex with RNA polymerase II elongation factor (ELL, MIM 600284) (Slagsvold et al., 2005 [PubMed 15755741], Kamura et al., 2001 [PubMed 11278625]).

Poids moléculaire: 29 kDa

ID gène: 11267

NCBI Accession: NP_009172

UniProt: Q96H20