TAB2 anticorps

N° du produit ABIN2460457

Cet anticorps Lapin Polyclonal détecte spécifiquement TAB2 dans WB, ELISA et IHC. Il présente une réactivité envers Humain, Souris, Rat et Chien.

Aperçu rapide pour TAB2 anticorps (ABIN2460457)

Antigène: TAB2 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))

Reactivité: Humain, Souris, Rat, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TAB2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-TAB2 anticorps

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human MAP3K7IP2.

Information d'application

Indications d'application: MAP3K7IP2 antibody can be used for detection of MAP3K7IP2 by ELISA at 1:312500. MAP3K7IP2 antibody can be used for detection of MAP3K7IP2 by western blot at 2.0/mL.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store MAP3K7IP2 antibody at -20 °C.

Détails sur TAB2

Antigène: TAB2 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))

Autre désignation: MAP3K7IP2

Sujet: MAP3K7IP2 is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of NF.:B and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serving as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF.:B (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.

Poids moléculaire: 76 kDa

ID gène: 23118

NCBI Accession: NP_055908

UniProt: Q9NYJ8

Pathways: TCR Signaling, Signalisation TLR, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway