ZIC2 anticorps

N° du produit ABIN2461223

Détail du produit anti-ZIC2 anticorps

Antigène: ZIC2

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ZIC2 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human ZIC2.

Information d'application

Indications d'application: ZIC2 antibody can be used for detection of ZIC2 by ELISA at 1:62500. ZIC2 antibody can be used for detection of ZIC2 by western blot at 0.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store ZIC2 antibody at -20 °C.

Détails sur ZIC2

Antigène: ZIC2

Autre désignation: ZIC2 (ZIC2 Produits)

Synonymes: anticorps HPE5, anticorps Ku, anticorps cb851, anticorps fb26a03, anticorps wu:fb26a03, anticorps zic2, anticorps zic2.1, anticorps hpe5, anticorps hm:zeh0655, anticorps id:ibd5017, anticorps zic2.2, anticorps zic2l, anticorps Zic family member 2, anticorps zinc finger protein of the cerebellum 2, anticorps zic family member 2 (odd-paired homolog, Drosophila), a, anticorps Zic family member 2 L homeolog, anticorps zic family member 2 (odd-paired homolog, Drosophila) b, anticorps ZIC2, anticorps Zic2, anticorps zic2a, anticorps zic2.L, anticorps zic2b

Sujet: ZIC2 is a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects.This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. This protein functions as a transcriptional repressor and may regulate tissue specific expression of dopamine receptor D1. Mutations in this gene cause holoprosencephaly type 5. Holoprosencephaly is the most common structural anomaly of the human brain. A polyhistidine tract polymorphism in this gene may be associated with increased risk of neural tube defects. This gene is closely linked to a gene encoding zinc finger protein of the cerebellum 5, a related family member on chromosome 13.

Poids moléculaire: 55 kDa

ID gène: 7546

NCBI Accession: NP_009060

UniProt: O95409

Pathways: Tube Formation