TIMELESS anticorps

N° du produit ABIN2461712

L’anticorps Lapin Polyclonal anti-TIMELESS a été validé pour WB et ELISA. Il convient pour détecter TIMELESS dans des échantillons de Humain et Chien.

Aperçu rapide pour TIMELESS anticorps (ABIN2461712)

Antigène: TIMELESS (Timeless Homolog (TIMELESS))

Reactivité: Humain, Chien

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TIMELESS est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-TIMELESS anticorps

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human TIMELESS.

Information d'application

Indications d'application: TIMELESS antibody can be used for detection of TIMELESS by ELISA at 1:312500. TIMELESS antibody can be used for detection of TIMELESS by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store TIMELESS antibody at -20 °C.

Détails sur TIMELESS

Antigène: TIMELESS (Timeless Homolog (TIMELESS))

Autre désignation: TIMELESS

Sujet: The human Timeless protein interacts with both the circadian clock protein cryptochrome 2 and with the cell cycle checkpoint proteins Chk1 and the ATR-ATRIP complex and plays an important role in the DNA damage checkpoint response. Down-regulation of Timeless in human cells seriously compromises replication and intra-S checkpoints, indicating an intimate connection between the circadian cycle and the DNA damage checkpoints that is in part mediated by the Timeless protein.

Poids moléculaire: 139 kDa

ID gène: 8914

NCBI Accession: NP_003911

UniProt: Q9UNS1

Pathways: Protein targeting to Nucleus, Photoperiodism