CSH1 anticorps

N° du produit ABIN2462104

Détail du produit anti-CSH1 anticorps

Antigène: CSH1 (Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CSH1 est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human CSH1.

Information d'application

Indications d'application: CSH1 antibody can be used for detection of CSH1 by ELISA at 1:312500. CSH1 antibody can be used for detection of CSH1 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store CSH1 antibody at -20 °C.

Détails sur CSH1

Antigène: CSH1 (Chorionic Somatomammotropin Hormone 1 (Placental Lactogen) (CSH1))

Autre désignation: CSH1 (CSH1 Produits)

Synonymes: anticorps CS-1, anticorps CSA, anticorps CSMT, anticorps PL, anticorps hCS-A, anticorps CS-2, anticorps CSB, anticorps hCS-B, anticorps chorionic somatomammotropin hormone 1, anticorps chorionic somatomammotropin hormone 2, anticorps CSH1, anticorps CSH2

Sujet: CSH1 is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome.The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation, an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome.

Poids moléculaire: 24 kDa, 15 kDa, 25 kDa, 25 kDa, 16 kDa, 23 kDa, 29 kDa, 19 kDa

ID gène: 1442

NCBI Accession: NP_001308

UniProt: P01243

Pathways: Response to Growth Hormone Stimulus