NXF3 anticorps

N° du produit ABIN2462273

Détail du produit anti-NXF3 anticorps

Antigène: NXF3 (Nuclear RNA Export Factor 3 (NXF3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NXF3 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human NXF3.

Information d'application

Indications d'application: NXF3 antibody can be used for detection of NXF3 by ELISA at 1:1562500. NXF3 antibody can be used for detection of NXF3 by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store NXF3 antibody at -20 °C.

Détails sur NXF3

Antigène: NXF3 (Nuclear RNA Export Factor 3 (NXF3))

Autre désignation: NXF3 (NXF3 Produits)

Synonymes: anticorps NXF3, anticorps Gm384, anticorps RGD1564923, anticorps nuclear RNA export factor 3, anticorps NXF3, anticorps LOC523530, anticorps LOC100060140, anticorps LOC100060240, anticorps LOC785244, anticorps Nxf3

Sujet: NXF3 is one member of a family of nuclear RNA export factors. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. NXF3 has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.

Poids moléculaire: 58 kDa, 72 kDa, 60 kDa, 72 kDa, 72 kDa, 72 kDa, 72 kDa, 28 kDa

ID gène: 56000

NCBI Accession: NP_071335

UniProt: Q9H4D5