COX15 anticorps

N° du produit ABIN2462983

Détail du produit anti-COX15 anticorps

Antigène: COX15 (Cytochrome C Oxidase Assembly Homolog 15 (COX15))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COX15 est non-conjugé

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human COX15.

Information d'application

Indications d'application: COX15 antibody can be used for detection of COX15 by ELISA at 1:62500. COX15 antibody can be used for detection of COX15 by western blot at 5.0 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store COX15 antibody at -20 °C.

Détails sur COX15

Antigène: COX15 (Cytochrome C Oxidase Assembly Homolog 15 (COX15))

Autre désignation: COX15 (COX15 Produits)

Synonymes: anticorps COX15, anticorps wu:fa18g06, anticorps zgc:56240, anticorps zgc:77422, anticorps 2900026G05Rik, anticorps CEMCOX2, anticorps COX15, cytochrome c oxidase assembly homolog, anticorps COX15 homolog, cytochrome c oxidase assembly protein (yeast), anticorps COX15 cytochrome c oxidase assembly homolog, anticorps cytochrome c oxidase assembly homolog 15 (yeast), anticorps cytochrome c oxidase assembly protein 15, anticorps cytochrome c oxidase assembly protein COX15 homolog, anticorps COX15, anticorps Cox15, anticorps cox15, anticorps LOC100410987, anticorps LOC100599631

Sujet: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane.Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be essential for the biogenesis of COX formation and may function in the hydroxylation of heme O, according to the yeast mutant studies. This protein is predicted to contain 5 transmembrane domains localized in the mitochondrial inner membrane. Alternative splicing of this gene generates several transcript variants diverging in the 3' region including alternate poly A sites. In total, 2 different isoforms are encoded by these variants.

Poids moléculaire: 44 kDa, 46 kDa

ID gène: 1355

NCBI Accession: NP_004367