PSMC3IP anticorps

N° du produit ABIN2463083

Détail du produit anti-PSMC3IP anticorps

Antigène: PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PSMC3IP est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PSMC3IP.

Information d'application

Indications d'application: PSMC3IP antibody can be used for detection of PSMC3IP by ELISA at 1:62500. PSMC3IP antibody can be used for detection of PSMC3IP by western blot at 1.25 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PSMC3IP antibody at -20 °C.

Détails sur PSMC3IP

Antigène: PSMC3IP (PSMC3 Interacting Protein (PSMC3IP))

Autre désignation: PSMC3IP (PSMC3IP Produits)

Synonymes: anticorps PSMC3IP, anticorps Arabidopsis Hop2 homolog, anticorps T6J4.9, anticorps T6J4_9, anticorps C79099, anticorps GT198, anticorps HOP2, anticorps Tbpip, anticorps HUMGT198A, anticorps ODG3, anticorps TBPIP, anticorps Gt198, anticorps zgc:86785, anticorps PSMC3 interacting protein, anticorps homologous-pairing protein 2 homolog, anticorps Homologous-pairing protein 2 homolog, anticorps homologous-pairing protein 2 homolog-like, anticorps Tat-binding protein 1(Tbp-1)-interacting protein (TBPIP), anticorps proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein, anticorps PSMC3 interacting protein L homeolog, anticorps PSMC3IP, anticorps LOC726449, anticorps LOC100165513, anticorps hop2, anticorps psmc3ip, anticorps LOC100633854, anticorps LOC100650062, anticorps LOC789362, anticorps AHP2, anticorps Psmc3ip, anticorps psmc3ip.L

Sujet: PSMC3IP plays an important role in meiotic recombination. It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis. The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA. This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA. This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing. It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.

Poids moléculaire: 25 kDa

ID gène: 29893

NCBI Accession: NP_057640

UniProt: Q9P2W1