PCMT1 anticorps

N° du produit ABIN2463200

Détail du produit anti-PCMT1 anticorps

Antigène: PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCMT1 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by protein A chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PCMT1.

Information d'application

Indications d'application: PCMT1 antibody can be used for detection of PCMT1 by ELISA at 1:312500. PCMT1 antibody can be used for detection of PCMT1 by western blot at 2.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 100 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store PCMT1 antibody at -20 °C.

Détails sur PCMT1

Antigène: PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))

Autre désignation: PCMT1 (PCMT1 Produits)

Synonymes: anticorps PIMT, anticorps C79501, anticorps PCM, anticorps PCMT, anticorps etID309741.20, anticorps fj13d06, anticorps pimt, anticorps wu:fj13d06, anticorps protein-L-isoaspartate (D-aspartate) O-methyltransferase, anticorps protein-L-isoaspartate (D-aspartate) O-methyltransferase 1, anticorps protein-L-isoaspartate (D-aspartate) O-methyltransferase L homeolog, anticorps protein-L-isoaspartate(D-aspartate)O-methyltransferase, anticorps PCMT1, anticorps Pcmt1, anticorps pcmt1.L, anticorps pcmt1, anticorps pcmt

Sujet: Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.Three classes of protein carboxyl methyltransferases, distinguished by their methyl-acceptor substrate specificity, have been found in prokaryotic and eukaryotic cells. The type II enzyme catalyzes the transfer of a methyl group from S-adenosyl-L-methionine to the free carboxyl groups of D-aspartyl and L-isoaspartyl residues. These methyl-accepting residues result from the spontaneous deamidation, isomerization, and racemization of normal L-aspartyl and L-asparaginyl residues and represent sites of covalent damage to aging proteins PCMT1 (EC 2.1.1.77) is a protein repair enzyme that initiates the conversion of abnormal D-aspartyl and L-isoaspartyl residues to the normal L-aspartyl form.[supplied by OMIM]. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Poids moléculaire: 25 kDa

ID gène: 5110

NCBI Accession: NP_005380

UniProt: P22061

Pathways: Ribonucleoprotein Complex Subunit Organization