SEMA6D anticorps

N° du produit ABIN2463280

Détail du produit anti-SEMA6D anticorps

Antigène: SEMA6D (Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6D (SEMA6D))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SEMA6D est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: Antibody is purified by peptide affinity chromatography method.

Immunogène: Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human SEMA6D.

Information d'application

Indications d'application: SEMA6D antibody can be used for detection of SEMA6D by ELISA at 1:312500. SEMA6D antibody can be used for detection of SEMA6D by western blot at 0.5 μg/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 50 ?L of distilled water. Final antibody concentration is 1 mg/mL.

Concentration: 1 mg/mL

Buffer: Antibody is lyophilized in PBS buffer with 2 % sucrose.

Conseil sur la manipulation: As with any antibody avoid repeat freeze-thaw cycles.

Stock: 4 °C/-20 °C

Stockage commentaire: For short periods of storage (days) store at 4 °C. For longer periods of storage, store SEMA6D antibody at -20 °C.

Détails sur SEMA6D

Antigène: SEMA6D (Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6D (SEMA6D))

Autre désignation: SEMA6D (SEMA6D Produits)

Synonymes: anticorps 1110067B02Rik, anticorps AA409156, anticorps D330011G23, anticorps Sema6D-1, anticorps Sema6D-2, anticorps Sema6D-4, anticorps Sema6D-5, anticorps Sema6D-6, anticorps mKIAA1479, anticorps wu:fi06a12, anticorps wu:fi76a10, anticorps zgc:56170, anticorps semaphorin 6D, anticorps sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D, anticorps semaphorin 6D L homeolog, anticorps SEMA6D, anticorps Sema6d, anticorps sema6d, anticorps sema6d.L

Sujet: Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphoring domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. SEMA6D is a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Six transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner.Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Six transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner.

Poids moléculaire: 52 kDa

ID gène: 80031

NCBI Accession: NP_079242

UniProt: Q8NFY4

Pathways: Smooth Muscle Cell Migration