SGK1 anticorps (AA 211-431)

N° du produit ABIN2468035

Cet anticorps Poulet Polyclonal détecte spécifiquement SGK1 dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour SGK1 anticorps (AA 211-431) (ABIN2468035)

Antigène: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Reactivité: Humain, Souris, Rat

Hôte: Poulet

Clonalité: Polyclonal

Conjugué: Cet anticorp SGK1 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-SGK1 anticorps

Épitope: AA 211-431

Purification: Immunoaffinity Purified

Information d'application

Indications d'application: Serine/threonine-protein kinase Sgk1 antibody can be used for the detection of Serine/threonine-protein kinase Sgk1 by Western Blot.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-Buffered Saline. No preservatives added.

Agent conservateur: Without preservative

Conseil sur la manipulation: As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

Stock: 4 °C/-20 °C

Stockage commentaire: SGK antibody can be stored at 4 °C for short term (weeks). Long term storage should be at -20 °C.

Détails sur SGK1

Antigène: SGK1 (serum/glucocorticoid Regulated Kinase 1 (SGK1))

Autre désignation: SGK

Sujet: FUNCTION: Protein kinase that plays an important role in cellular stress response. Activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. Sustained high levels and activity may contribute to conditions such as hypertension and diabetic nephropathy. Mediates cell survival signals, phosphorylates and negatively regulates pro-apoptotic FOXO3A. Phosphorylates NEDD4L, which leads to its inactivation and to the subsequent activation of various channels and transporters such as ENaC, Kv1.3, or EAAT1.

Poids moléculaire: 49 kDa (calculated)

ID gène: 6446

NCBI Accession: NP_005618

UniProt: O00141

Pathways: Signalisation MAPK, Signalisation Notch, Steroid Hormone Mediated Signaling Pathway