Insulin Receptor anticorps (Internal Region)

N° du produit ABIN2469537

Cet anticorps anti-Insulin Receptor est un anticorps Lapin Polyclonal détectant Insulin Receptor dans IHC. Adapté pour Humain, Singe, Gibbon et Gorilla.

Aperçu rapide pour Insulin Receptor anticorps (Internal Region) (ABIN2469537)

Antigène: Insulin Receptor (INSR)

Reactivité: Humain, Singe, Gibbon, Gorilla

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Insulin Receptor est non-conjugé

Application: Immunohistochemistry (IHC)

Détail du produit anti-Insulin Receptor anticorps

Épitope: Internal Region

Specificité: BLAST analysis of the peptide immunogen showed no homology with other human proteins, except JARID2 (69 % ).

Purification: Immunoaffinity Chromatography

Immunogène: Insulin Receptor antibody was raised against a peptide located near the internal domain of Insulin Receptor (Human).

Information d'application

Indications d'application: Insulin Receptor antibody can be used in ELISA starting at 1:10000, and immunohistochemistry starting at 1:200 - 1:400.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS, 0.1 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: As with all antibodies avoid freeze/thaw cycles.

Stock: 4 °C/-80 °C

Stockage commentaire: Insulin Receptor antibody should be stored long term (months) at -80 °C and short term (days) at 4 °C.

Détails sur Insulin Receptor

Antigène: Insulin Receptor (INSR)

Autre désignation: Insulin Receptor

Sujet: INSR is an insulin receptor type protein kinase. Binding of insulin to INSR stimulates glucose uptake. Two insulin receptor mRNA transcripts resulting from alternative splicing of exon 11 in the receptor gene are expressed in a highly regulated tissue-specific fashion. Mutations in the INSR gene contribute to diseases, including of various forms of insulin resistance, insulin-resistant diabetes mellitus, noninsulin-dependent diabetes mellitus (NIDDM), Rabson-Mendenhall syndrome and Leprechaunism (Donohue Syndrome).

ID gène: 3643

UniProt: P06213

Pathways: Signalisation NF-kappaB, Signalisation RTK, AMPK Signaling, Carbohydrate Homeostasis, Regulation of Cell Size, Regulation of Carbohydrate Metabolic Process, Growth Factor Binding, Negative Regulation of Transporter Activity