CD28 anticorps

N° du produit ABIN2479686

Cet anticorps anti-CD28 est un anticorps Souris Monoclonal détectant CD28 dans FACS et Func. Adapté pour Souris. Ce Primary Antibody a été cité dans 3+ publications.

Aperçu rapide pour CD28 anticorps (ABIN2479686)

Antigène: CD28

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD28 est non-conjugé

Application: Flow Cytometry (FACS), Functional Studies (Func)

Clone: E18

Détail du produit anti-CD28 anticorps

Attributs du produit: Purified IgG

niveau d'endotoxine: Low endotoxin

Immunogène: Alternate immunisation with A20 cells expressing mCD28 and recombinant mCD28Ig.

Isotype: IgG2b

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1.0 mg/mL

Références pour anticorps anti-CD28 (ABIN2479686)

Gogishvili, Lühder, Kirstein, Nieuwenhuizen, Goebbels, Beer-Hammer, Pfeffer, Reuter, Taube, Brombacher, Hünig: "Interruption of CD28-mediated costimulation during allergen challenge protects mice from allergic airway disease." dans: The Journal of allergy and clinical immunology, Vol. 130, Issue 6, pp. 1394-403.e4, (2012) (PubMed).

Beyersdorf, Ding, Blank, Dennehy, Kerkau, Hünig: "Protection from graft-versus-host disease with a novel B7 binding site-specific mouse anti-mouse CD28 monoclonal antibody." dans: Blood, Vol. 112, Issue 10, pp. 4328-36, (2008) (PubMed).

Dennehy, Elias, Zeder-Lutz, Ding, Altschuh, Lühder, Hünig: "Cutting edge: monovalency of CD28 maintains the antigen dependence of T cell costimulatory responses." dans: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 10, pp. 5725-9, (2006) (PubMed).

Détails sur CD28

Antigène: CD28

Autre désignation: CD28

ID gène: 12487

UniProt: P31041

Pathways: TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response