Biliverdin Reductase anticorps (Biotin)

N° du produit ABIN2482108

Détail du produit anti-Biliverdin Reductase anticorps (Biotin)

Antigène: Biliverdin Reductase (BLVRA) (Biliverdin Reductase A (BLVRA))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Biliverdin Reductase est conjugé à/à la Biotin

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Specificité: Detects ~36 kDa.

Réactivité croisée: Humain, Souris, Rat

Purification: Protein A Purified

Immunogène: Rat native full-length BVR purified from liver tissue

Information d'application

Indications d'application:

• WB (1:500)
• IHC (1:1000)
• IP (1:100)
• optimal dilutions for assays should be determined by the user.

Commentaires:

2 μg/ml of ABIN2482108 was sufficient for detection of BVR in 20 μg of mixed human cell line lysate by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Conjugated antibodies should be stored at 4°C

Détails sur Biliverdin Reductase

Antigène: Biliverdin Reductase (BLVRA) (Biliverdin Reductase A (BLVRA))

Autre désignation: BVR (BLVRA Produits)

Synonymes: anticorps blvra, anticorps MGC69310, anticorps BLVRA, anticorps zgc:153046, anticorps BVR, anticorps Dmel\\CG9471, anticorps BLVR, anticorps BVRA, anticorps 0610006A11Rik, anticorps 2500001N03Rik, anticorps Blvr, anticorps biliverdin reductase A, anticorps biliverdin reductase A L homeolog, anticorps CG9471 gene product from transcript CG9471-RA, anticorps BLVRA, anticorps blvra, anticorps blvra.L, anticorps CG9471, anticorps Blvra

Sujet: Biliverdin Reductase (BVR) is a cytoplasmic enzyme that catalyzes the conversion of biliverdin to bilirubin by converting a double bond between the second and third pyrrole ring into a single bond (1). It is ubiqutiously expressed in all tissues- it occurs in cells and brain regiuons that already display HO-1 and HO-2, but also in regions and cell types with potential to induce stress proteins. It is unique among all enzymes in having two pH optima, using a different cofactor at each pH range, NADH at pH 7.0 and NADPH at pH 8.7 (2). It is not inactivated by heat shock, and have shown to abate inflammation, oxidative stress and apoptosis (3).

ID gène: 116599

NCBI Accession: NP_446302

UniProt: P46844