MDC1 anticorps (N-Term) (Atto 390)

N° du produit ABIN2484141

Cet anticorps Souris Monoclonal détecte spécifiquement MDC1 dans WB, IF et ICC. Il présente une réactivité envers Souris.

Aperçu rapide pour MDC1 anticorps (N-Term) (Atto 390) (ABIN2484141)

Antigène: MDC1 (Mdc1 (MDC1))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MDC1 est conjugé à/à la Atto 390

Application: Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC)

Clone: P2B11

Détail du produit anti-MDC1 anticorps (Atto 390)

Épitope: N-Term

Specificité: Detects ~184 kDa. This antibody recognizes MDC1 at and around the N-terminus.

Réactivité croisée: Chimpanzé, Boeuf (Vache), Humain, Souris

Purification: Protein G Purified

Immunogène: GST-tagged recombinant protein corresponding to mouse MDC1 at and around the N-terminus

Isotype: IgG1

Information d'application

Indications d'application:

• WB (1:2000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Commentaires:

0.5 μg/ml of ABIN2484141 was sufficient for detection of MDC1 in 10 μg of HeLa cell lysate by ECL immunoblot analysis.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Conjugated antibodies should be stored at 4°C

Détails sur MDC1

Antigène: MDC1 (Mdc1 (MDC1))

Autre désignation: MDC1

Sujet: MDC1, mediator of DNA damage checkpoint protein 1, plays a role in checkpoint mediated cell cycle arrest in response to DNA damage, within S phase and G2/M. It is also thought to act as a scaffold protein during recruitment of DNA repair and signal transduction proteins to discrete foci of DNA damage that are marked by phosphorylation of histone H2A.X on S139.

ID gène: 240087

NCBI Accession: NP_001010833

UniProt: Q5PSV9