KCNJ8 anticorps (AA 306-424) (FITC)

N° du produit ABIN2485711

Détail du produit anti-KCNJ8 anticorps (FITC)

Antigène: KCNJ8 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 8 (KCNJ8))

Épitope: AA 306-424

Reactivité: Rat

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp KCNJ8 est conjugé à/à la FITC

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)

Specificité: Detects ~45 kDa.

Réactivité croisée: Humain, Souris, Rat

Purification: Protein G Purified

Immunogène: Fusion protein amino acids 306-424 (Cytoplasmic C-terminus) of rat Kir6.1

Clone: S366-60

Isotype: IgG2a

Information d'application

Indications d'application:

• WB (1:1000)
• ICC/IF (1:100)
• optimal dilutions for assays should be determined by the user.

Commentaires:

A 1:100 dilution of ABIN2485711 was sufficient for detection of Kir6.1 in 20 μg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: PBS pH 7.4, 50 % glycerol, 0.1 % sodium azide, Storage buffer may change when conjugated

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Conjugated antibodies should be stored at 4°C

Détails sur KCNJ8

Antigène: KCNJ8 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 8 (KCNJ8))

Autre désignation: Kir6.1 (KCNJ8 Produits)

Synonymes: anticorps kir6.1, anticorps KIR6.1, anticorps uKATP-1, anticorps AI448900, anticorps Kir6.1, anticorps gnite, anticorps slmbr, anticorps sltr, anticorps UKATP1, anticorps si:dkey-183c2.2, anticorps zkir6.1, anticorps potassium voltage-gated channel subfamily J member 8, anticorps potassium channel, inwardly rectifying subfamily J, member 8, anticorps potassium inwardly-rectifying channel, subfamily J, member 8, anticorps potassium channel, inwardly rectifying subfamily J, member 8 S homeolog, anticorps KCNJ8, anticorps kcnj8, anticorps Kcnj8, anticorps kcnj8.S

Sujet: Several different potassium channels are known to be involved with electrical signaling in the nervous system. One class is activated by depolarization whereas a second class is not. The latter are referred to as inwardly rectifying K+ channels, and they have a greater tendency to allow potassium to flow into the cell rather than out of it. This asymmetry in potassium ion conductance plays a key role in the excitability of muscle cells and neurons. The protein encoded by this gene is an integral membrane protein and member of the inward rectifier potassium channel family (1-3). This is predominantly detected in fetal and adult hearts, and defects can be associated with J-wave syndromes, a group of heart disorders characterized by early repolarization events (4).

ID gène: 25472

NCBI Accession: NP_058795

UniProt: Q63664