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TLR4 anticorps (AA 420-435) (FITC)

TLR4 Reactivité: Humain WB, FACS, IHC, IF, ICC Hôte: Lapin Polyclonal FITC
N° du produit ABIN2485972
  • Antigène Voir toutes TLR4 Anticorps
    TLR4 (Toll-Like Receptor 4 (TLR4))
    Épitope
    • 16
    • 16
    • 16
    • 15
    • 13
    • 8
    • 7
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 420-435
    Reactivité
    • 181
    • 101
    • 75
    • 37
    • 23
    • 20
    • 19
    • 19
    • 5
    • 2
    • 1
    • 1
    Humain
    Hôte
    • 138
    • 74
    • 8
    • 4
    Lapin
    Clonalité
    • 142
    • 82
    Polyclonal
    Conjugué
    • 99
    • 24
    • 20
    • 16
    • 9
    • 7
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TLR4 est conjugé à/à la FITC
    Application
    • 161
    • 130
    • 60
    • 56
    • 35
    • 32
    • 27
    • 27
    • 26
    • 24
    • 13
    • 8
    • 8
    • 8
    • 5
    • 5
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    Specificité
    Detects ~75-80 kDa when tested against partial recombinant mouse TLR4 (extra-cellular portion plus His-tag).
     Réactivité croisée
    Humain, Souris
    Purification
    Protein A Purified
    Immunogène
    Developed against a synthetic peptide corresponding to amino acids 420-435 of human TLR4
    Top Product
    Discover our top product TLR4 Anticorps primaire
  • Indications d'application
    • WB (1:500)
    • IHC (1:50)
    • optimal dilutions for assays should be determined by the user.
    Commentaires

    2 μg/ml of ABIN2485972 was sufficient for detection of TLR4 in 100 ng of partial recombinant mouse TLR4 protein by colorimetric immunoblot analysis using Goat anti-rabbit IgG:HRP as the secondary antibody.

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS, 50 % glycerol, 0.09 % sodium azide, Storage buffer may change when conjugated
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    4 °C
    Stockage commentaire
    Conjugated antibodies should be stored at 4°C
  • Antigène
    TLR4 (Toll-Like Receptor 4 (TLR4))
    Autre désignation
    TLR4 (TLR4 Produits)
    Synonymes
    anticorps ARMD10, anticorps CD284, anticorps TLR-4, anticorps TOLL, anticorps Lps, anticorps Ly87, anticorps Ran/M1, anticorps Rasl2-8, anticorps toll like receptor 4, anticorps toll-like receptor 4, anticorps TLR4, anticorps Tlr4
    Sujet
    The Toll-like receptor (TLR) family in mammal comprises a family of trans-membrane proteins characterized by multiple copies of leucine rich repeats in the extracellular domain and 1L-1 receptor motif in the cytoplasmic domain. Like its counterparts in Drosophila, TLRs signal through adaptor molecules (1). The TLR family is a phylo-genetically conserved mediator of innate immunity that is essential for microbial recognition (2). Ten human homologs of TLRs (TLR1-10) have been described (3). Amount this family of receptors, TLR2 and TLR4 have been most studied. These studies have suggested that TLR2 and TLR4 may serve as potential main mediators of LPS signaling (4,5). The mouse TLR4 cDNA codes for a protein consisting of 839 amino acids, with an approximate molecular weight of 90 kDa (6).
    ID gène
    7099
    NCBI Accession
    NP_612564
    UniProt
    O00206
    Pathways
    Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Toll-Like Receptors Cascades, Inflammasome, S100 Proteins
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