CD51/CD61 anticorps

N° du produit ABIN2567844

Détail du produit anti-CD51/CD61 anticorps

Antigène: CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD51/CD61 est non-conjugé

Application: Flow Cytometry (FACS), Functional Studies (Func)

Specificité: The 23C6 monoclonal antibody specifically reacts with the human CD51/61 Molecule, known as the integrin alpha v Beta 3 complex or vitronectin receptor.

Purification: The monoclonal antibody was purified utilizing affinity chromatography. The endotoxin level is determined by LAL test to be less than 0.01 EU/μg of the protein.

Clone: 23C6

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: Phosphate-buffered aqueous solution, ph7.2.

Stock: 4 °C

Stockage commentaire: The product should be stored undiluted at 4°C. Do not freeze.

Détails sur CD51/CD61

Antigène: CD51/CD61 (ITGAV/ITGB3) (Integrin AlphaV, Integrin Beta3 (ITGAV/ITGB3))

Autre désignation: CD51/CD61 (ITGAV/ITGB3 Produits)

Synonymes: anticorps CD51, anticorps MSK8, anticorps VNRA, anticorps VTNR, anticorps integrin subunit alpha V, anticorps ITGAV

Sujet: The 23C6 monoclonal antibody specifically reacts with the human CD51/61 Molecule, known as the integrin alpha v Beta 3 complex or vitronectin receptor. The complex binds to other ligands such as CD29, fibrinogen, fibrinectin, vWf, laminin, and thrombospondin. It is expressed by endothelial cells, osteoclasts, melanoma cells, and at low levels on platelets and macrophages. The 23C6 antibody is reported to be able to block the receptors ability to form interactions with some of its ligands.

ID gène: 3685, 3690

UniProt: P06756, P05106