VTI1B anticorps

N° du produit ABIN2568531

Détail du produit anti-VTI1B anticorps

Antigène: VTI1B (Vesicle Transport through Interaction with T-SNAREs Homolog 1B (VTI1B))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp VTI1B est non-conjugé

Application: Western Blotting (WB), ELISA

Specificité: VTI1b antibody is human, mouse and rat reactive. At least three isoforms of VTI1a are known to exist, this antibody will detect all three isoforms. VTI1b antibody is predicted to not cross-react with VTI1a.

Purification: VTI1b antibody is affinity chromatography purified via peptide column.

Immunogène: VTI1b antibody was raised against a 17 amino acid peptide near the center of human VTI1b.

Isotype: IgG

Information d'application

Indications d'application: VTI1b antibody can be used for detection of VTI1b by Western blot at 1 - 2 μ,g/mL.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: VTI1b antibody is supplied in PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C,4 °C

Stockage commentaire: VTI1b antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Détails sur VTI1B

Antigène: VTI1B (Vesicle Transport through Interaction with T-SNAREs Homolog 1B (VTI1B))

Autre désignation: VTI1b (VTI1B Produits)

Synonymes: anticorps VTI1, anticorps VTI1-LIKE, anticorps VTI1L, anticorps VTI2, anticorps v-SNARE, anticorps vti1-rp1, anticorps AU015348, anticorps GES30, anticorps MVti1b, anticorps SNARE, anticorps Vti1-rp1, anticorps zgc:63525, anticorps VTI1B, anticorps vesicle transport through interaction with t-SNAREs 1B, anticorps vesicle transport through interaction with t-SNAREs 1B pseudogene, anticorps VTI1B, anticorps Vti1b, anticorps vti1b, anticorps LOC461624

Sujet: Vesicle transport through interaction with t-SNAREs homolog 1 (VTI1a and VTI1b) are involved in vesicular transport from the late endosomes to the trans-Golgi network (1). They are both localized in the trans-Golgi network, with VTI1a also found in the Golgi apparatus and VTI1b in endosomes (2,3). It is thought that VTI1b along with the SNARE protein VAMP8 mediates the fusion of antimicrobial and canonical autophagosomes with lysosomes, an essential process for autophagy (4).

Poids moléculaire: Predicted: 14, 19, 26 kDa

Observed: 27 kDa

ID gène: 10490

NCBI Accession: NP_006361

UniProt: Q9UEU0