Neuregulin 1 anticorps (AA 617-636)
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- Antigène Voir toutes Neuregulin 1 (NRG1) Anticorps
- Neuregulin 1 (NRG1)
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Épitope
- AA 617-636
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Reactivité
- Humain, Singe
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp Neuregulin 1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
- Specificité
- Type I isoforms are the predominant forms expressed in the endocardium. Isoform alpha is expressed in breast, ovary, testis, prostate, heart, skeletal muscle, lung, placenta liver, kidney, salivary gland, small intestine and brain, but not in uterus, stomach, pancreas, and spleen. Isoform 3 is the predominant form in mesenchymal cells and in non-neuronal organs, whereas isoform 6 is the major neuronal form. Isoform 8 is expressed in spinal cord and brain. Isoform 9 is the major form in skeletal muscle cells, in the nervous system it is expressed in spinal cord and brain. Also detected in adult heart, placenta, lung, liver, kidney, and pancreas. Isoform 10 is expressed in nervous system: spinal cord motor neurons, dorsal root ganglion neurons, and brain. Predominant isoform expressed in sensory and motor neurons. Not detected in adult heart, placenta, lung, liver, skeletal muscle, kidney, and pancreas. Not expressed in fetal lung, liver and kidney. Type IV isoforms are brain-specific. .
- Réactivité croisée (Details)
- No cross reactivity with other proteins.
- Purification
- Immunogen affinity purified
- Immunogène
- A synthetic peptide corresponding to a sequence at the C-terminus of human NRG1(617-636aa RFSTQEEIQARLSSVIANQD), different from the related rat and mouse sequences by one amino acids.
- Isotype
- IgG
- Top Product
- Discover our top product NRG1 Anticorps primaire
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- Indications d'application
- Optimal working dilution should be determined by the investigator.
- Commentaires
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Target Species of Antibody: Human
- Restrictions
- For Research Use only
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- Format
- Liquid
- Reconstitution
- Distilled water
- Concentration
- Lot specific
- Buffer
- Contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2 HPO4, 0.05 mg Thimerosal, 0.05 mg sodium azide per 100 μg antibody.
- Agent conservateur
- Sodium azide, Thimerosal (Merthiolate)
- Précaution d'utilisation
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- At -20°C for 1 year. After reconstitution, at 4°C for 1 month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid freeze-thaw cycles.
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- Antigène
- Neuregulin 1 (NRG1)
- Autre désignation
- NRG1 / Heregulin / Neuregulin (NRG1 Produits)
- Synonymes
- anticorps 6030402G23Rik, anticorps ARIA, anticorps D230005F13Rik, anticorps GGF, anticorps GGFII, anticorps HRG, anticorps HRGalpha, anticorps Hgl, anticorps NDF, anticorps SMDF, anticorps GGF2, anticorps HGL, anticorps HRG1, anticorps HRGA, anticorps MST131, anticorps NRG-1, anticorps heregulin, anticorps nrg1-A, anticorps pro-neuregulin-1, anticorps NRG1, anticorps wu:fm70e01, anticorps DKFZp459A1838, anticorps neuregulin 1, anticorps histidine rich glycoprotein, anticorps neuregulin 1 L homeolog, anticorps Nrg1, anticorps NRG1, anticorps HRG, anticorps nrg1.L, anticorps nrg1
- Sujet
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Name/Gene ID: NRG1
Synonyms: NRG1, ARIA, GGF, GGF2, Glial growth factor, Heregulin, HRGA, MSTP131, NDF, Neu differentiation factor, Neuregulin 1 type IV beta 3, Neuregulin 1 type IV beta 1a, HRG1, NRG-1, SMDF, Neuregulin 1, Pro-NRG1, HGL, MST131 - ID gène
- 3084
- Pathways
- Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Muscle Cell Differentiation
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