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AKAP12 anticorps (AA 620-1596)

AKAP12 Reactivité: Rat, Boeuf (Vache) WB, IP, IHC (fro) Hôte: Mouton Polyclonal unconjugated
N° du produit ABIN264964
  • Antigène Voir toutes AKAP12 Anticorps
    AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))
    Épitope
    • 4
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 620-1596
    Reactivité
    • 22
    • 4
    • 3
    • 2
    Rat, Boeuf (Vache)
    Hôte
    • 20
    • 3
    • 2
    • 2
    Mouton
    Clonalité
    • 26
    • 1
    Polyclonal
    Conjugué
    • 20
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp AKAP12 est non-conjugé
    Application
    • 14
    • 9
    • 9
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Purification
    Ammonium Sulfate Precipitation.
    Immunogène
    Recombinant protein corresponding to amino acids 620-1596 of the SSeCKS protein.
    Isotype
    IgG
    Top Product
    Discover our top product AKAP12 Anticorps primaire
  • Indications d'application
    Western Blot: 2-5 μg/mL. Immunoprecipitation. Immunohistochemistry.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline with 0.08 % Sodium Azide as preservative.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    -20 °C
    Stockage commentaire
    The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.
  • Antigène
    AKAP12 (A Kinase (PRKA) Anchor Protein 12 (AKAP12))
    Autre désignation
    AKAP12 / SSeCKS (AKAP12 Produits)
    Synonymes
    anticorps akap12, anticorps cb27, anticorps esr1, anticorps fb72g12, anticorps id:ibd1202, anticorps sb:cb27, anticorps si:ch73-192g21.1, anticorps wu:fb72g12, anticorps wu:fc21c03, anticorps AKAP12, anticorps AI317366, anticorps SSeCKS, anticorps Srcs5, anticorps Tsga12, anticorps AKAP12A, anticorps AKAP12B, anticorps AKAP12G, anticorps AKAP250, anticorps A kinase (PRKA) anchor protein 12b, anticorps A-kinase anchoring protein 12, anticorps A kinase (PRKA) anchor protein (gravin) 12, anticorps akap12b, anticorps AKAP12, anticorps Akap12
    Sujet
    Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation and proliferation, yet little is known about downstream substrates or their roles in normal or diseased states. SSeCKS, a novel protein kinase C substrate originally isolated as a src-suppressed negative mitogenic regulator in fibroblasts, controls actinbased cytoskeletal architecture and scaffolds key signaling kinases such as protein kinase C and protein kinase A. Activation of protein kinase C is a key signal transduction event in mesangial cell dedifferentiation. A role for SSeCKS, a PKA/PKC scaffolding protein, has been implicatedduring the process of spermiogenesis and in the actinbased stellate morphology of mesangial cells.
    ID gène
    10116
    UniProt
    Q62766
    Pathways
    cAMP Metabolic Process
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