ARHGEF2 anticorps (AA 2-447)

N° du produit ABIN264980

Détail du produit anti-ARHGEF2 anticorps

Antigène: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Épitope: AA 2-447

Reactivité: Souris

Hôte: Mouton

Clonalité: Polyclonal

Conjugué: Cet anticorp ARHGEF2 est non-conjugé

Application: Western Blotting (WB), Immunoprecipitation (IP), Immunofluorescence (IF)

Specificité: This antibody recognizes LCF.

Purification: Purified

Immunogène: Antibody developed using protein corresponding to amino acids 2 to 447 of the Lfc protein fused to GST.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 4 μg/mL, Detects a 118 kDa band in mouse tissue extracts corresponding towild-type Lfc. Immunoprecipitation: 4 μg/mL. Immunofluorescence.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate Buffered Saline and 0.08 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Détails sur ARHGEF2

Antigène: ARHGEF2 (rho/rac Guanine Nucleotide Exchange Factor (GEF) 2 (ARHGEF2))

Autre désignation: ARHGEF2 (ARHGEF2 Produits)

Synonymes: anticorps MGC82333, anticorps MGC86214, anticorps MGC75855, anticorps AA408978, anticorps GEF, anticorps GEF-H1, anticorps GEFH1, anticorps LFP40, anticorps Lbcl1, anticorps Lfc, anticorps P40, anticorps mKIAA0651, anticorps GEF-H1/LFC, anticorps Rho/Rac guanine nucleotide exchange factor 2, anticorps Rho/Rac guanine nucleotide exchange factor 2 S homeolog, anticorps rho/rac guanine nucleotide exchange factor (GEF) 2, anticorps ARHGEF2, anticorps arhgef2.S, anticorps arhgef2, anticorps Arhgef2

Sujet: Lfc is a 118 kDa protein discovered in a screen for oncogenes in NIH 3T3 cells. Lfc is a signaling protein related to Lbc and is part of the Dbl family of proteins. Lfc is a guanine-nucleotide exchange factor (GEF) for the Rho family of small GTPases. Lfc has also been shown to be upstream of the serine-threonine kinase JNK. Lfc has also been shown to mediate the activation of the Rac signaling pathway.Synonyms: GEF-H1, Guanine nucleotide exchange factor H1, KIAA0651, LFP40, Microtubule-regulated Rho-GEF, Proliferating cell nucleolar antigen p40, Rho guanine nucleotide exchange factor 2

ID gène: 16800

NCBI Accession: NP_001185840

UniProt: Q60875

Pathways: Negative Regulation of intrinsic apoptotic Signaling