CACNA1A anticorps

N° du produit ABIN265030

Détail du produit anti-CACNA1A anticorps

Antigène: CACNA1A (Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CACNA1A est non-conjugé

Application: Western Blotting (WB)

Purification: Purified

Immunogène: Synthetic peptide derived from the rat alpha1A calcium channel conjugated to KLH.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 5 - 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Détails sur CACNA1A

Antigène: CACNA1A (Calcium Channel, Voltage-Dependent, P/Q Type, alpha 1A Subunit (CACNA1A))

Autre désignation: CACNA1A (CACNA1A Produits)

Synonymes: anticorps cav2.1, anticorps cacna-a, anticorps ca(v)2.1, anticorps cacna1a, anticorps si:ch211-237k17.1, anticorps BccA1, anticorps Cav2.1, anticorps rbA-1, anticorps APCA, anticorps BI, anticorps CACNL1A4, anticorps CAV2.1, anticorps EA2, anticorps FHM, anticorps HPCA, anticorps MHP, anticorps MHP1, anticorps SCA6, anticorps Caca1a, anticorps Cacnl1a4, anticorps Ccha1a, anticorps alpha1A, anticorps la, anticorps leaner, anticorps nmf352, anticorps rkr, anticorps rocker, anticorps tg, anticorps tottering, anticorps CACH4, anticorps CACN3, anticorps calcium channel, voltage-dependent, P/Q type, alpha 1A subunit S homeolog, anticorps calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, a, anticorps calcium voltage-gated channel subunit alpha1 A, anticorps calcium channel, voltage-dependent, P/Q type, alpha 1A subunit, anticorps P/Q-type voltage-gated calcium channel alpha1A subunit ChCaChA1A, anticorps cacna1a.S, anticorps cacna1aa, anticorps CACNA1A, anticorps Cacna1a, anticorps LOC395892

Sujet: Voltage-sensitive calcium channels (VSCCs) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1a gives rise to p and/or q-type calcium currents. P/q-type calcium channels belong to the 'high-voltage activated' (hva) group and are blocked by the funnel toxin (ftx) and by the omega-agatoxin-IVA (omega-aga-IVA). They are however insensitive to dihydropyridines (dhp), and omega- conotoxin-GVIA (omega-ctx-GVIA). voltage-dependent calcium channels are multisubunit complexes, consisting of alpha-1, alpha-2, beta and delta subunits in a 1:1:1:1 ratio. The channel activity is directed by the poreforming and voltage-sensitive alpha-1 subunit. In many cases, this subunit is sufficient to generate voltage-sensitive calcium channel activity. The auxiliary subunits beta and alpha-2/delta linked by a disulfide bridge regulate the channel activity.Synonyms: Brain calcium channel I, CACH4, CACN3, CACNL1A4, Calcium channel L type alpha-1 polypeptide isoform 4, Cav2.1, Voltage-dependent P/Q-type calcium channel subunit alpha-1A, Voltage-gated calcium channel subunit alpha

ID gène: 10116

UniProt: P54282

Pathways: Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process