TICAM2 anticorps (C-Term)

N° du produit ABIN265137

Cet anticorps anti-TICAM2 est un anticorps Lapin Polyclonal détectant TICAM2 dans WB et IHC (fro). Adapté pour Humain.

Aperçu rapide pour TICAM2 anticorps (C-Term) (ABIN265137)

Antigène: TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TICAM2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-TICAM2 anticorps

Épitope: C-Term

Specificité: This antibody reacts to Toll-like Receptor Adaptor Protein (TIRP) (CT).

Purification: Purified

Immunogène: Rabbit polyclonal TIRP antibody was raised against a peptide corresponding to amino acids at the C-terminus of human TIRP.

Isotype: IgG

Information d'application

Indications d'application: Western Blot: 0.5 to 2 μg/mL. Immunohistochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Stockage commentaire: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Détails sur TICAM2

Antigène: TICAM2 (Toll-Like Receptor Adaptor Molecule 2 (TICAM2))

Autre désignation: TICAM2 / TRAM

Sujet: TIRP is a member of the Toll/interleukin-1 receptor (TIR) family, a group of proteins that include the Toll-like receptors (TLRs) (1 - 3). TLRs are signaling molecules that recognize different pathogenassociated molecular patterns (PAMPs) and serve as an important link between the innate and adaptive immune responses (4). TIRP, along with other molecules such as TRIF, MAL, and MyD88, serves as an adaptor protein that allows for the interaction and activation of the IL-1R-associated kinase (IRAK) family, the subsequent activation of TNF receptor associated factor (TRAF)-6, and ultimately the activation of NF-?B (5). Expression of TIRP appears to be essential for TLR4 signalling (6).Synonyms: Putative NF-kappa-B-activating protein 502, TICAM-2, TIR domain-containing adapter molecule 2, TIRAP3, TIRP, TRIF-related adapter molecule, Toll-like receptor adaptor protein 3, Toll/interleukin-1 receptor domain-containing protein

ID gène: 100302736

NCBI Accession: NP_001157941

UniProt: Q86XR7

Pathways: Signalisation TLR, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades