PTPN13 anticorps

N° du produit ABIN265414

Détail du produit anti-PTPN13 anticorps

Antigène: PTPN13 (Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTPN13 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody detects endogenous levels of PTPN13 / FAP-1 protein (region surrounding Lys366).

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Affinity chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: ELISA: 1/10000-1/20000. Western Blot: 1/500-1/2000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PTPN13

Antigène: PTPN13 (Protein tyrosine Phosphatase, Non-Receptor Type 13 (APO-1/CD95 (Fas)-Associated Phosphatase) (PTPN13))

Autre désignation: PTPN13 (PTPN13 Produits)

Synonymes: anticorps FAP-1, anticorps PNP1, anticorps PTP-BAS, anticorps PTP-BL, anticorps PTP1E, anticorps PTPL1, anticorps PTPLE, anticorps hPTP1E, anticorps PTPN13, anticorps AI324989, anticorps Ptpri, anticorps RIP, anticorps Ptp-bl, anticorps ptp, anticorps wu:fb50g04, anticorps zgc:162319, anticorps protein tyrosine phosphatase, non-receptor type 13, anticorps tyrosine-protein phosphatase non-receptor type 13, anticorps PTPN13, anticorps LOC100540743, anticorps ptpn13, anticorps Ptpn13

Sujet: Fibroblast Activation Protein alpha subunit (FAPa or FAP, alpha) is a integral membrane gelatinase belonging to the serine protease family. FAPa is the alpha subunit and DPP4 (CD26) the beta subunit of a heterodimeric membrane-bound proteinase complex also known as 170 kDa Melanoma Membrane Gelatinase, Integral Membrane Serine Proteinase and Seprase,which also has subunit molecular weight as 88 kDa,95 kDa, 97 kDa. Some cells make only FAPa homodimers, some only DPP4 homodimers. The monomer is inactive. FAP, alpha is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis.Synonyms: FAP1, Fas-associated protein-tyrosine phosphatase 1, PNP1, PTP-BAS, PTP-E1, PTP1E, PTPL1, Protein-tyrosine phosphatase 1E, Protein-tyrosine phosphatase PTPL1, Tyrosine-protein phosphatase non-receptor type 13

Poids moléculaire: approx. 88 kDa

ID gène: 5783

NCBI Accession: NP_006255

UniProt: Q12923