GZMB anticorps (Alexa Fluor 647)

N° du produit ABIN2657899

L’anticorps anti-GZMB Monoclonal produit chez le Souris a été validé pour FACS. Il convient pour la détection de GZMB dans des échantillons provenant de Humain et Souris. }

Aperçu rapide pour GZMB anticorps (Alexa Fluor 647) (ABIN2657899)

Antigène: GZMB (Granzyme B (GZMB))

Reactivité: Humain, Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp GZMB est conjugé à/à la Alexa Fluor 647

Application: Flow Cytometry (FACS)

Clone: GB11

Détail du produit anti-GZMB anticorps (Alexa Fluor 647)

Réactivité croisée: Rat (Rattus)

Purification: The antibody was purified by affinity chromatography, and conjugated with Alexa Fluor® 647 under optimal conditions.

Isotype: IgG1 kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C

Détails sur GZMB

Antigène: GZMB (Granzyme B (GZMB))

Autre désignation: Granzyme B

Sujet: Granzyme B is a 32 kD serine protease, also known as granzyme-2, serine protease B, CCP1, Asp-ase, and CTLA-1. Granzyme B is abundantly stored in the granules of cytotoxic T lymphocytes and NK cells. Low level of expression has been reported in granulocytes, B cells, and activated dendritic cells. Granzyme B is crucial for rapid induction of cell death and apoptosis through interaction with mannose-6-phosphate receptor.

Pathways: Apoptose, Caspase Cascade in Apoptosis