CLEC12A anticorps (PE)

N° du produit ABIN2662631

Détail du produit anti-CLEC12A anticorps (PE)

Antigène: CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))

Reactivité: Souris

Hôte: Rat

Clonalité: Monoclonal

Conjugué: Cet anticorp CLEC12A est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Purification: The antibody was purified by affinity chromatography and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Clone: 5D3-CLEC12A

Isotype: IgG2a kappa

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Protect from prolonged exposure to light. Do not freeze.

Stock: 4 °C

Stockage commentaire: The antibody solution should be stored undiluted between 2°C and 8°C.

Détails sur CLEC12A

Antigène: CLEC12A (C-Type Lectin Domain Family 12, Member A (CLEC12A))

Autre désignation: CD371 (CLEC12A Produits)

Synonymes: anticorps MGC179455, anticorps CLL-1, anticorps CLL1, anticorps DCAL-2, anticorps MICL, anticorps D230024O04, anticorps KLRL1, anticorps Micl, anticorps C-type lectin domain family 12 member A, anticorps C-type lectin domain family 12, member a, anticorps C-type lectin domain family 12, member A, anticorps CLEC12A, anticorps Clec12a

Sujet: CD371 (CLEC12A), also known as DCAL-2, MICL or CLL-1, is a 30 kD type II transmembrane protein with extracellular C-type lectin domains, belonging to the C-type lectin family. Its cytoplasmic ITIM motif modulates signaling cascades and is involved in phosphorylation of tyrosine residues in MAP kinases. Mouse CLEC12A is expressed on CD8 + dendritic cells (DCs), a proportion of CD8- dendritc cells, plasmacytoid DCs, monoctyes, macrophages, granulocytes, and B cells.